用PCR方法检测婴儿肝炎综合征患婴的HCMV感染情况  

Detection of Cytomegalovirus in Children Infected Infant Hepatitis Syndrome by Using Polymerase Chain Reaction

作　　者：赵国强[1] 程勉学[1] 石秀兰[1] 郭超[1] 阮丽荣[1] 

机构地区：[1]河南医科大学微生物学教研室,郑州市儿童医院

出　　处：《胃肠病学和肝病学杂志》1995年第3期194-195,共2页Chinese Journal of Gastroenterology and Hepatology

摘　　要：两年来收集到婴儿肝炎综合征患婴（１５～１８０天）共６２例。用ＰｏｌｙｍｅｒａｓｅＣｈａｉｎｒｅａｃｔｉｏｎ（ＰＣＲ）方法检测尿标本中的ＨＣＭＶＤＮＡ。结果显示：阳性率为４５．２％（２８／６２）；并且１月内患婴的阳性率（６０％）明显高于１～６月患婴（３１．３％）。提示Ｃｙｔｏｍａｇａｌｏｖｉｒｕｓ（ＨＣＭＶ）是引起婴儿肝炎综合征的主要病原，并且在１月内患婴中是首要病原。infants (15～180 days)infected infant hepatitis syndrome were collected in the past two years. Their urine samples have been detected of cytomegalovirus by polmerase chain reaction. The results showed that the positive rate was 45.2%(28/62);the positive rate (60%)for baby younger than one month is higher than that for baby 1～6 months(31.3%).The results indicate that cytomegalovirus was the major pathogen of infant hepatitis syndrome.

关 键 词：婴儿肝炎综合征 HCMV PCR 

分 类 号：R725.126[医药卫生—儿科]