他扎罗汀凝胶与卡泊三醇软膏治疗斑块型银屑病的比较  

Tazarotene gel vs calcipotriol ointment in treating plaque-type psoriasis

作　　者：李惠[1] 李桂明[1] 周汛[1] 饶静[1] 何晓琴[1] 陈家秀[1] 赖松青[1] 肖元福[1] 

机构地区：[1]重庆医科大学附属第一医院皮肤科,重庆400016

出　　处：《中国新药与临床杂志》2002年第3期155-158,共4页Chinese Journal of New Drugs and Clinical Remedies

摘　　要：目的 :观察他扎罗汀凝胶治疗斑块型银屑病的疗效与安全性 ,并与卡泊三醇软膏比较。方法 :71例斑块型银屑病病人分为 2组 ,他扎罗汀组 36例 ,每晚外涂 1次 ;卡泊三醇组 35例 ,早、晚各外涂1次 ,2组疗程均为 12wk。结果 :2组的总有效率分别为 83%和 79% ,差异无显著意义 (P >0 .0 5 )。结论 :他扎罗汀凝胶治疗斑块型银屑病安全有效 。AIM: To observe the efficacy and safety of tazarotene gel in the treatment of plaque type psoriasis and compare with calcipotriol ointment. METHODS: Seventy one patients with plaque type psoriasis were divided into two groups. Thirty six patients were treated with tazarotene gel topically qn for 12 wk. Thirty five patients were treated with calcipotriol ointment topically q12 h for 12 wk. RESULTS: In both tazarotene group and calcipotriol group, the total effective rates were 83 % and 79 % respectively. There were no obvious differences between the two groups( P >0.05). CONCLUSION: Tazarotene gel is similar to calcipotriol ointment, safe and effective in therapy for plaque type psoriass.

关 键 词：他扎罗汀 银屑病 卡泊三醇 药物评价 慢性复发性红斑鳞屑性皮肤病 

分 类 号：R986[医药卫生—药品] R758.63[医药卫生—药学]