梅毒治疗过程中吉海反应相关因素分析  

Related factors of Jarisch-Herxheimer reaction during the treatment of syphilis

作　　者：章伟[1] 陈霞凤[1] 丁杨峰[1] 顾志英[1] 张刚[1] 

机构地区：[1]上海市皮肤病性病医院,上海200050

出　　处：《临床皮肤科杂志》2002年第3期141-142,共2页Journal of Clinical Dermatology

摘　　要：为了探讨吉海反应的相关因素。在梅毒患者首次治疗后,观察记录不良反应并作统计学处理。结果表明吉海反应的发生率与性别相关(OR=3.016可信区间1.539～5.910),与梅毒的分类相关(OR1=2.889可信区间1.380～6.046,OR2=2.726可信区间1.248～5.953),与年龄、体重、是否妊娠、RPR滴度和治疗药物等因素无关。结论认为男性较女性容易发生反应,显性梅毒的发生率高于潜伏梅毒。This study was to explore the related factors of Jarisch Herxheimer reaction. After the initial treatment,the side effects in these patients were observed, recorded and analyzed. The results showed that the incidence of Jarisch Herxheimer reaction is directly related to gender(OR=3.016 confidence interval 1.539～5.910). It is also correlated to the types and classification of syphilis(OR1=2.889 confidence interval 1.380～6.046, OR2=2.726 confidence interval 1.248～5.953). It is no correlation with age, body weight, pregnancy, RPR titer or medication. Male patient is easier to develope Jarisch Herxheimer reaction than female patient. The Jarisch Herxheimer reaction in dominant syphilis is much higher than in latent syphilis.

关 键 词：梅毒 吉海反应 相关因素 治疗过程 

分 类 号：R759.1[医药卫生—皮肤病学与性病学]