硫酸氢钾催化合成氯乙酸异丙酯  

Synthesis of Isopropyl Chloroacetate using Potassium Bisulfate as Catalyst

作　　者：刘国华[1] 朱孝蓉[1] 储开华[1] 钱越[1] 

机构地区：[1]盐城工学院化工系,江苏盐城224003

出　　处：《化学世界》2002年第3期153-154,共2页Chemical World

摘　　要：以自制的硫酸氢钾为催化剂合成了氯乙酸异丙酯 ,最高产率为 87.4%。该反应操作简单 ,催化剂价廉易得 ,不溶于反应体系 ,可过滤回收 ,重复使用 ,产率几乎不变。Isopropyl chloroacecate, was synthesized using potassium bisulfate as catalyst. The highest yield of the reactioin can reach 87.4%. potassium bisurfate is not only cheap and easy to get, but also insoluble in the reaction system. It can be recovered by filtration and reused. The product yield is almost unchanged on reused catalyst.

关 键 词：硫酸氢钾 氯乙酸异丙酯 催化合成 萘普生 布洛芬 原料 

分 类 号：TQ463.2[化学工程—制药化工]