施普瑞螺旋藻对尾吊模拟失重大鼠肠道微生态失调的调整作用研究  

STUDY ON THE EFFECTS OF SPIRULINA ON MICRODYSBIOSIS IN RAT'S GUT UNDER SIMULATED WEIGHTLESSNESS

作　　者：白树民[1] 黄纪明[1] 胡志祥 杨春雷 李志霞[1] 朱德兵[1] 洪建武[1] 梁明[3] 熊德鑫[3] 

机构地区：[1]航天医学工程研究所,北京100094 [2]云南施普瑞有限责任公司 [3]解放军304医院创伤研究室

出　　处：《中国微生态学杂志》2002年第1期5-7,共3页Chinese Journal of Microecology

摘　　要：目的 :研究模拟失重条件下 ,施普瑞螺旋藻对大鼠肠道微生态失调的调整作用。方法 :将基础饲料中加入 5 %的螺旋藻作为处理组饲喂大鼠 ,用选择性培养基分别对肠球菌、肠杆菌、类杆菌、乳杆菌以及双歧杆菌定量测定 ,扫描电镜观察大鼠盲肠上皮细胞的组织变化。结果 :螺旋藻处理组过路菌群中肠杆菌和肠球菌数量变化并不明显 ;原籍菌群中双歧杆菌较对照组显著增多 ,类杆菌和乳杆菌的数量差异没有显著性。模拟失重条件下 SD大鼠盲肠上皮有肿胀细胞出现 ,并且肠道上皮绒毛排列紊乱、稀疏 ,而螺旋藻处理组中只发现有少量的肿胀细胞 ,上皮绒毛致密、排列较整齐。结论 :旋普瑞螺旋藻具有纠正在模拟失重条件下大鼠肠道微生态平衡失调的作用。Objective:To investigate adjustive effects of spirulina on the microecology in rats gestrointestinal under simulated weightlessness Methods: Selective culture media were used to culture Enterococcus,Enterobacteria,Bacteroid,Lactobacillus and Bifidobacteria respectively;scan electron microscope was used to observe the changes of SD rat's caecum mucosa epithelia Results: Under the same condition,the numbers of Enterococcus and Enterobacteria were altered slightly and Bifidobateria increased markedly in spirulina tratment group compared with the to control;only a few tumefacient cell were observed in rat's caecum mucosa epithelia and the epithelia villus of caecum Conclusion: Spirulina has adjustive effects on the gut microflora of rat simulated weightlessness

关 键 词：螺旋藻 模拟失重 微生态失调 大鼠肠道 调整作用 

分 类 号：R852.22[医药卫生—航空、航天与航海医学] R977.9[医药卫生—临床医学]