胰体康胶囊治疗2型糖尿病125例临床研究  

Clinical observation of Yitikang capsule on type 2 diabetes millitus

作　　者：龚振岭 靳国春 康胜群[2] 李立[3] 张秀菊 

机构地区：[1]河北省正定县中医研究所附属医院,正定050810 [2]河北医科大学第三医院,石家庄050051 [3]河北省医学科学院,石家庄050021 [4]河北省正定县人民医院,石家庄050810

出　　处：《河北中医》2002年第2期83-86,共4页Hebei Journal of Traditional Chinese Medicine

摘　　要：目的　观察胰体康胶囊治疗 2型糖尿病的临床疗效。方法　治疗组 1 2 5例 ,口服胰体康胶囊 ,每次 4粒 ,每日 3次。对照组 30例 ,口服参芪降糖胶囊 ,每次 4粒 ,每日 3次。 2组均连续用药 3个月 ,监测 2组治疗前后空腹及餐后 2h血糖、糖化血红蛋白、血脂、血液流变学和血胰岛素水平 ,血胰岛素水平较高者检测血胰岛素受体水平。结果　与对照组比较 ,治疗组临床症状改善明显 ,空腹血糖、餐后 2h血糖、糖化血红蛋白 ,胆固醇、甘油三酯以及血浆黏度、红细胞压积及纤维蛋白原明显降低 (P <0 .0 1或P <0 .0 5 ) ,且治疗组对胰岛素水平低者有升高作用 (P <0 .0 5 ) ,高者有轻度降低作用 (P <0 .0 5 )。治疗后胰岛素受体数目增多 ,亲和力增加 (P <0 .0 5 )。结论　胰体康胶囊具有改善临床症状、降糖、降脂及改善血流变学的作用 ,治疗Objective To observe clinical effect of Yitikang capsule on type 2 diabetes millitus. Methods 155 patients with type 2 diabetes millitus were divided into treatment group (n=125), which was treated by Yitikang capsule, and control group (n=30) which was treated by shen qi jiang tang capsule. Blood glucose, HbA1c, blood lipid, hemorheology and blood insulin level fasting and postprandial 2hr in both groups were detected. Results Levels of Blood glucose of Fasting and postprandial 2hr, HbA1c, cholesterol, triglyceride, hematocrit and fibrinogen were significantly lower  (P<0.05)  than those in control group. Conclusion Yitikang capsule can produce obvious effect on the treatment of type 2 diabetes millitus.

关 键 词：2型糖尿病 胰体康胶囊 血糖 胰岛素 血脂 血流变学 糖化血红蛋白 临床研究 中医药疗法 治疗 

分 类 号：R259.871[医药卫生—中西医结合] R286.715[医药卫生—中医内科学]