活血通痹袋泡剂的质量标准研究  

Studies on Quality Standard of Huoxue Tongbi Bagged Steep

作　　者：夏华玲[1] 赵新杰[1] 李军红[1] 杜志谦[1] 许保军[1] 

机构地区：[1]河南省洛阳正骨医院正骨研究所,洛阳471002

出　　处：《中药新药与临床药理》2002年第1期30-40,共11页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：河南省科技攻关项目 (编号 :95A 32 11)

摘　　要：目的建立活血通痹袋泡剂的质量控制标准。方法采用薄层色谱法 (λ=36 5nm)对其中羌活、五加皮进行了定性鉴别 ,并用薄层扫描法 (反射法单波长锯齿扫描 ,线性参数SX =3,λ =5 0 0nm)对丹参中丹参酮ⅡA进行含量测定。结果鉴别项下的阴性对照无干扰 ,专属性强 ;丹参酮ⅡA在 0 .1～ 1.6 μg间有良好的线性关系(r=0 .9990 ) ,平均回收率为 10 2 .7% ,RSD为 2 .38%。Objective: To set up the standard for the quality control of Huoxue Tongbi bagged steep. Methods: Rhizoma seu Radix Notopterygii, Cortex Acanthopanacis Radicis were verified by TLC and TanshinoneⅡA was determined by TLCS (Sx=3,λ=500nm). Results: The TLC spots were highly specific, clear and concentrated without interference of the presence of negative controls. Concentration curve of TanshinoneⅡA showed a good linearity within the range of 0.1 ～ 1.6 μg,r = 0.9990, average recovery rate was 102.7%, and RSD= 2.38%. Conclusion: This method can be used for the quality control of Huoxue Tongbi steep.

关 键 词：活血通痹袋泡剂 丹参酮ⅡA 羌活 五加皮 薄层色谱法 中药 

分 类 号：R286.0[医药卫生—中药学]