老年颈动脉硬化与血脂及载脂蛋白AI对比研究  

Comparison study of Gerontal Carotid Arteriosclerosis with Plasma Lipoprotein and Apolipoprotein AI

作　　者：杨小端[1] 温建中[1] 李萍[1] 蒋冀玲[1] 

机构地区：[1]江西医学院第三附属医院,南昌市330008

出　　处：《中国超声医学杂志》2002年第2期120-121,共2页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 :探讨颈动脉硬化与血液中脂类成分的关系。方法 :用二维超声观察及测量颈动脉内膜 -中层厚度 (IMT)及斑块的形成 ,同时抽血检查血脂及载脂蛋白。结果 :颈动脉硬化者血脂及载脂蛋白除载脂蛋白 AI(apo AI)明显降低外 ,其它均正常。颈动脉硬化与 Apo AI呈强负相关。颈动脉斑块组 :血 apo AI较正常组下降 6 .3% ,颈动脉管壁增厚组 :较正常下降 4 .3% ,具有非常显著性差异 (P<0 .0 1)。结论 :颈动脉硬化时血 apo AI明显低于正常组 ,且这两项检测均为无创检查 ,对脑血管病变的预后。Objective:To assess the correlation of carotid arteriosclerosis with plasma lipoprotein.Methods:Carotid intima media thickness and carotid vascular plaque were detected by two dimensional ultrasound mean while plasma Lipoprotein and apolipoprotein were tested.Results:Plasma Lipoprotein and apolipoprotein were normal except that apolipoprotein AI was reducted.Carotid arteriosclerosis was inversely corrleated with apolipoprotein AI(apoAI).In the carotid arteriosclerosis group plasma apoAI was 6 3% lower than that in mormal group,In carotid vascular hypertrophy group it was 4 3% lower than that in normal group.There was an cvidcnt diffcrcncc bctwccn them. P <0 01.Conclusions:In carotid arteriosclcrosis,apoAI result a more significant reduction than it does normally.Besides the two non injury test echniques,it has clinical value in prediction and treatment of cerebrovascular disease.

关 键 词：颈动脉硬化 二维超声 载脂蛋白AI 血脂 老年人 对比研究 

分 类 号：R445.1[医药卫生—影像医学与核医学]