“养肝柔筋方”对大鼠耐运动性疲劳能力和血清、股四头肌AChE活性的影响  

The Influence of "Yang Gan Rou Jin Fang"(Prescription of Nourishing the Liver and Tendon) on Rat's Ability of Bearing Sports Fatigue and the Activity of Acetylcholinesterase (AChE) in Serum and Quadriceps Femoris

作　　者：马玉兰 胡利民[2] 史丽萍[2] 马东明[2] 马艳[2] 

机构地区：[1]山西省运城市中心医院,044000 [2]天津中医学院,300193

出　　处：《天津中医》2002年第2期46-48,共3页Tianjin Journal of Traditional Chinese Medicine

基　　金：天津市高等教育局科研资助课题 (97531)

摘　　要：目的 :探讨“养肝柔筋方”抗运动性疲劳作用的现代机制。方法 :选用游泳训练导致大鼠运动性疲劳模型 ,用生化检测方法 ,研究运动大鼠血清和股四头肌中胆碱酯酶 (AChE)活性的变化 ,及“养肝柔筋方”对其变化的影响。结果 :与安静对照组比较 ,运动性疲劳组大鼠血清和股四头肌中AChE活性均降低(P<0 01) ,而灌胃“养肝柔筋方”组大鼠血清和股四头肌中AChE活性均提高 (P<0 01)。结论 :“养肝柔筋方”可显著提高大鼠运动状态下血清和股四头肌中AChE活性 ,这可能是该方抗运动性疲劳的机制之一。Objective: To research the modern mechanism of the effect of 'Yang Gan Rou Jin Fang' (Prescription of Nourishing the Liver and Tendom) on bearing sports fatigue in rats. Methods: Using rat's model of swimming training-induced sports fatigue and biochemical examination the activity changes of AChE in serum and quadriceps femoris were determined in fatigued rats and the influence of 'Yang Gan Rou Jin Fang' on them was observed. Results: Compared with the rest rats in control group the AChE activities of serum and quadriceps femoris in fatigue group were reduced(P<0.01). However, the indices in treated rats by ingestion of Yang Gan Rou Jin Fang were significantly increased. Conclusion: Yang Gan Rou Jin Fang could markedly increase the AChE activity of serum and quadriceps femoris in exercise state This might be one of the mechanisms of anti-sport fatigue action of this prescription.

关 键 词：运动性疲劳 养肝柔筋方 股四头肌 胆碱酯酶活性 中医药疗法 治疗 大鼠 

分 类 号：R285.5[医药卫生—中药学]