中药血清药化学与中药血清药理学协同研究方法初探  

Study on Co-operation between Pharmacology of Serum with Chinese Drugs (PSCD) and Pharmic Chemistry of Serum with Chinese Drugs (PCSCD)

作　　者：杨奎 郭力[1] 周明眉[1] 姜远平[1] 王一涛[1] 蒲旭峰 李萍 陈槐卿[3] 吴立志 

机构地区：[1]成都中医药大学 [2]成都市药品检验所 [3]华西医科大学

出　　处：《中药药理与临床》1998年第4期41-44,共4页Pharmacology and Clinics of Chinese Materia Medica

基　　金：国家自然科学基金

摘　　要：采用ＨＰＬＣ二级管阵列检测法建立川芎不同提取物的血清指纹图谱，用１４Ｃ５ＨＴ释放法和４５Ｃａ掺入法测定相应含药血清的抗血小板释放５ＨＴ作用和阻滞血管内皮细胞钙通道作用，分析比较两者之间的关系，探索开展中药血清药化学与中药血清药理学协同研究的方法。? The finger chromatographies of serum with Abstracts from Lisgusticum chuanxiong Hort.were charted by HPLC with diodelogic.The effects of the serum,antirelease of 5-HT from platelet and inhibiting Ca^2+ transport toward rabbit blood endotheliocytus,were studied by the method of PSCD.Compared of these results,this paper explored the co-operation methods between PSCD and PCSCD.

关 键 词：中药血清药化学 中药血清药理学 抗血小板释放5-HT作用 钙通道阻滞作用 川芎 HPLC二级管阵列检测法 ^14C-5HT释放法 ^45Ca掺入法 血清指纹图谱 

分 类 号：R285[医药卫生—中药学] R282.71[医药卫生—中医学]