丹参对烯丙醇小鼠肝损伤修复过程中AgNORs的动态影响  

Dynamic Effects of Salvia Miltiorrhiza on AgNORs in Hepatic Cells in the Process of Hepatic Injury and Repair

作　　者：朱建伟[1,2,3] 张庆慧[1,2,3] 郑广娟[1,2,3] 李红 吕莉莉[1,2,3] 

机构地区：[1]山东省中医药研究所病理科 [2]山东医科大学病理解剖教研室 [3]山东中医药大学病理教研室

出　　处：《中药药理与临床》1998年第5期21-23,共3页Pharmacology and Clinics of Chinese Materia Medica

摘　　要：用烯丙醇制成大鼠肝损伤模型，观察了丹参在损伤修复过程中对细胞核内ＡｇＮＯＲｓ数目的动态影响。结果显示：与模型对照组相比，丹参可使损伤周围残存的肝细胞内的ＡｇＮＯＲｓ数目很快增多，坏死区很快由再生的肝细胞填充。The experimental hepatic injury in mice was induced by allyl alcohol(AA).Dynamic effects were studied about Salvia miltiorrhiza (SM) on AgNORs in hepatic cells in the process of injury and repair.It was shown that the number of AgNORs in SM group increased faster than that in control group.Necrosis areas in this group were filled up with regenerated hepatic cells mainly other than fibrous granulation as in control group.This indicated that promoting the preliferative activity of hepatic cells near injured areas may be one of the hepatic protecting mechanism of SM.

关 键 词：丹参 肝损伤 AGNORS 动态影响 烯丙醇 保肝作用 护肝机理 

分 类 号：R282.710.5[医药卫生—中药学]