不同干燥方法对远志筒及根中主要化学成分的影响  

Effects of different drying methods on active constituents of root bark and root of Polygala tenuifolia

作　　者：彭亮[1] 杨冰月[1] 程虎印[1] 张岗[1] 孙涛[1] 张明英 杨新杰[1] 刘阿萍[1] 颜永刚[1] 胡本祥[1] PENG Liang;YANG Bing-yue;CHENG Hu-yin;ZHANG Gang;SUN Tao;ZHANG Ming-ying;YANG Xin-jie;LIU A-ping;YAN Yong-gang;HU Ben-xiang(College of Pharmacy,Shaanxi University of Chinese Medicine,Xi'an 712046,China)

机构地区：[1]陕西中医药大学药学院,陕西西安712046

出　　处：《中草药》2018年第21期5010-5017,共8页Chinese Traditional and Herbal Drugs

基　　金：公益性行业(中医药)科研专项经费项目(201507002);国家大学生创新计划(201710716011);陕西省高校青年杰出人才支持计划项目;咸阳市中青年科技领军人才项目

摘　　要：目的考察晒干、阴干、热风干燥(40、50、60、70℃)、微波干燥和冷冻干燥5种干燥方法对远志筒及根中主要化学成分的影响。方法运用HPLC法测定不同干燥方法对远志筒及根中远志酮III、3,6′-二芥子酰基蔗糖、远志酸、远志皂苷元、细叶远志皂苷的组成和含量变化;采用单因素方差分析和TOPSIS法对数据进行综合分析。结果远志筒和根的干燥方法优选顺序存在差异,远志筒不同干燥方法对有效成分影响的优劣排序为微波干燥>60℃热风干燥>50℃热风干燥>70℃热风干燥>冷冻干燥>40℃热风干燥>阴干>晒干;远志根中,不同干燥方法的排序为微波干燥>60℃热风干燥>阴干>晒干>50℃热风干燥>40℃热风干燥>70℃热风干燥>冷冻干燥。结论结合生产实践,微波干燥和60℃热风干燥是远志筒和根较适宜的干燥方法,可为远志不同规格药材产地干燥方式的确定提供依据。Objective To investigate the effects of different drying methods on composition and content of five active constituents in root bark and root of Polgala tenuifoliaroot.Methods The contents ofpolygalaxanthone Ⅲ,3,6'-disinapoyl sucrose,polygalacic acid, senegenin,and tenuifolin in root bark and root from different drying samples were determined by HPLC.Then the data analysis was performedby ANOVA and TOPSIS methods.Results There is a difference in the order of drying methods for bark and root of P. tenuifoliaroot.For P.tenuifoliaroot root bark,the order of different drying methods was microwave drying >60℃ hot-air drying > 50℃ hot-air drying >70℃ hot-air drying >freeze-drying >40℃ hot-air drying >shade drying >sun drying;For P.tenuifolia root,the different drying methods were sorted by microwave drying >60℃ hot-air drying >shade drying >sun drying >50℃ hot-air drying >40℃ hot-air drying >70℃ hot-air drying >freeze-drying.Conclusion Combined with the production practice, this study suggests that microwave drying and hot-air drying at 60℃ are suitable drying methods for P.tenuifoliaroot bark and root, providing a basis for the determination of drying methods for the origin processing of P.tenuifolia.

关 键 词：远志 干燥方法 远志[口山]酮Ⅲ 3 6’一二芥子酰基蔗糖 远志酸 远志皂苷元 细叶远志皂苷 

分 类 号：R282.4[医药卫生—中药学]