广州居民血脂异常患病情况及相关因素分析  

The prevalence and correlative factors of dislipidemia in Guangzhou

作　　者：王培[1] 李奇观[1] 陈晓彤[1] 陈庆瑜[1] 孙润陆[2] WANG Pei;LI Qi-guan;CHEN Xiao-tong;CHEN Qing-yu;SUN Run-lu(Department of Medical examination center,Sun Yat -sen Memorial Hospital,Sun Yat -sen University,Guangzhou 510120,Guangdong,China)

机构地区：[1]中山大学孙逸仙纪念医院博济医疗中心,广东广州510120 [2]中山大学孙逸仙纪念医院心血管内科,广东广州510120

出　　处：《广东医学》2018年第22期3395-3398,共4页Guangdong Medical Journal

基　　金：国家自然科学基金资助项目(编号:81700397)

摘　　要：目的了解广州地区居民血脂异常患病情况并分析其相关因素。方法选取2013—2017年28 480例广州地区居民的健康体检数据,采用χ~2检验和非条件logistic回归模型对广州居民血脂异常相关因素进行分析。结果广州地区居民血脂异常总患病率为41. 31%,男性患病率(49. 28%)高于女性(33. 06%)(P <0. 01)。老年居民患病率(48. 43%)高于非老年居民(40. 82%)(P <0. 01)。χ~2检验结果显示,性别、年龄、体质指数(BMI)、收缩压、舒张压、腰围、血尿酸、空腹血糖等指标是血脂异常的相关因素(P <0. 01)。logistic回归分析结果显示,性别、腰围、血尿酸值与血脂异常存在关联(P <0. 05);与女性居民相比,男性居民患血脂异常的风险是女性居民的1. 717倍(P=0. 004);与腰围正常居民相比,腰围增大居民患血脂异常的风险是其1. 710倍(P=0. 021);与正常血尿酸居民相比,患高尿酸血症居民患血脂异常的风险是正常血尿酸居民1. 505倍(P=0. 031)。结论广州地区血脂异常患者主要为男性,有腰围增大、高尿酸血症的居民患血脂异常可能性较大,需要引起重视。Objective To investigate the prevalence of dislipidemia upon physical examination of Guangzhou residents,and its correlation factors.Methods A total of 28 480 resident who received physical examinations at Sun Yat-sen Memorial Hospital in Guangzhou,China from January 2013 to December 2017 were retrospectively enrolled in the study.The χ~2 test and unconditional logistic regression model were applied for analysis.Results The overall prevalence rate of dyslipidemia was 41.31%,it was significantly higher in male(49.28%) than female(33.06%,P < 0.01);higher in old(48.43%) than young participants(40.82%,P < 0.01).Results from χ~2 test showed that gender,age,body mass index,blood pressure,waist circumference,serum uric acid,and fasting glucose were significantly associated with dyslipidemia(P < 0.01).Logistic regression analysis showed that gender,waist circumference,and serum uric acid were significantly associated with dyslipidemia(P < 0.05).Male,increased waist circumference and serum uric acid were the independent risk factors of dislipidemia(P < 0.05).Conclusion A high prevalence(41.3%) of dyslipidemia was detected upon physical examination in Guangzhou.The main correlation factors of dyslipidemia were gender,waist circumference and serum uric acid concentration.

关 键 词：血脂异常 患病率 相关因素 

分 类 号：R589.2[医药卫生—内分泌]