益气活心丸治疗慢性心力衰竭随机对照临床研究  

Randomized controlled clinical study on Yiqi Huoxin Pill in the treatment of chronic heart failure

作　　者：王博雯[1] 张策 高奋堂[1] 李燕玲[1] 张福[1] 谢萍[1] WANG Bo-wen;ZHANG Ce;GAO Fen-tang;LI Yan-ling;ZHANG Fu;XIE Ping(Gansu Provincial Hospital,Lanzhou.730000,China)

机构地区：[1]甘肃省人民医院,兰州730000

出　　处：《中华中医药杂志》2018年第12期5721-5723,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：甘肃省重点中医药科技项目课题(No.GZK-2010-5)~~

摘　　要：目的:观察益气活心丸治疗慢性心力衰竭的疗效及安全性。方法:按照患者就诊顺序将162例慢性心力衰竭患者随机分为治疗组81例、对照组81例,疗程4周,观察纽约心功能分级、Lee’s心力衰竭积分、中医证候积分、左室射血分数和脑钠肽(BNP)疗效指标及安全性指标。结果:治疗组心功能显效率、总有效率明显高于对照组(P<0.05)。治疗后两组心功能好转,Lee’s心衰积分、中医证候疗效、左室射血分数、BNP疗效指标、安全性分析均改善(P<0.05);治疗组改善更明显(P<0.05)。结论:益气活心丸对治疗慢性心力衰竭具有良好的疗效及安全性,有效地改善患者临床症状及生活质量。Objective:To observe the efficacy and safety of Yiqi Huoxin Pill in the treatment of chronic heart failure (CHF).Methods:According to the order of treatment,162 patients with chronic heart failure were randomly divided into treatment group 81 and control group 81.The course of treatment was 4 weeks.The New York heart function classification,Lee's heart failure score,TCM symptom score,quality of life score and left ventricular ejection fraction and BNP index of curative effect and safety index were observed.Results:The effective and total effective rate of the treatment group was significantly higher than that of the control group (P<0.05).After treatment,the heart function,Lee's heart failure score,TCM syndrome effect,left ventricutar ejection fraction and safety analysis in the two groups were improved (P<0.05),and the treatment group improved more significantly (P<0.05).Conclusion:Yiqi Huoxin Pill has good efficacy and safety in the treatment of chronic heart failure, and it can effectively improve the clinical symptoms and quality of life,and reduce the hospitalization rate.

关 键 词：益气活心丸 慢性心力衰竭 临床研究 

分 类 号：R259[医药卫生—中西医结合]