小儿过敏性紫癜与肺炎支原体IgM阳性及C反应蛋白水平的临床分析  

Clinical Analysis of IgM and C-Reactive Protein Levels in Children with Allergic Purpura and Mycoplasma Pneumonia

作　　者：彭昭虹 陈宁 PENG Zhao-hong;CHEN Ning(Paediatrics Department ofLiupanshui People's Hospital,Liupanshui,Guizhou,553001)

机构地区：[1]六盘水市人民医院儿科,贵州六盘水553001

出　　处：《智慧健康》2018年第30期9-10,共2页Smart Healthcare

摘　　要：目的分析HSP与MP及CRP水平的关系,探讨小儿过敏性紫癜感染后M(IgM)、CRP检测的意义。方法选取我院于2017年03月至2018年03月收治的80例HSP患儿为研究对象,随机分为观察组与对照组2组,各40例。观察组主要对不同年龄阶段及不同发病季节患儿的MP-IgM阳性率、血清CRP水平进行检测,对照组主要对40例体检的无感染性疾病患儿的MP-IgM抗体的阳性率及血清CRP水平进行检测,然后对比两组患儿MP-IgM阳性率、血清CRP水平及观察组患儿在不同年龄阶段、不同发病季节下的MP-IgM阳性率。结果观察组MP-IgM阳性率62.36%高于对照组的7.45%;观察组CRP水平(19.36±12.24)mg/L高于对照组(6.12±4.37)mg/L,差异明显(P<0.05)。1-2月发病时,观察组MP-IgM阳性率79.34%高于3-4、11-12月份发病时MPIgM阳性率的43.12%和49.14%,10-12岁患儿MP-IgM阳性率76.4%大于年龄分别为3-5岁及8岁-10岁患儿MP-IgM阳性率的44.5%和46.8%,差异明显(P<0.05),有统计学意义。结论 MP感染会导致小儿HSP感染,不同季节、年龄下,患儿MP-IgM阳性率指标差异较大,检测患儿MP-IgM阳性率、血清CRP水平,可为HSP诊断提供参考。Objective to analyze the relationship between HSP and MP and CRP, and to explore the significance of detection of M(IgM) and CRP after allergic purpura infection in children. Methods 80 children with HSP admitted to our hospital from March 2017 to March. 2018 were selected as study objects, and were randomLy divided into observation group and control group, with 40 cases each. The observation group mainly tested the positive rate of MP- IgM and the serum CRP level of the children at different age stages and different disease seasons. The control group mainly tested positive rate of MP- IgM antibody and serum CRP level in 40 children with non-infectious diseases examined. Then, MP- IgM positive rate, serum CRP level and MP- IgM positive rate were compared between the two groups in different age stages and different onset seasons. Results the positive rate of MP- IgM in the observation group was 62.36% higher than that of the control group (7.45%).The CRP level of the observation group (19.36 ± 12.24) mg/L was higher than that of the control group (6.12 ± 4.37)mg/L, with significant differences (p<0.05). At the onset of 1-2 months, the positive rate of MP- IgM in the observation group was 79.34% higher than that of 43.12% and 49.14% in the onset of MP- IgM between 3-4 months and 11-12 months. The positive rate of MP- IgM in children aged 10-12 years was 76.4% higher than that in children aged 3-5 years and 8-10 years, 44.5% and 46.8% respectively, showing a significant difference (P<0.05), and statistical significance. Conclusion MP infection can lead to HSP infection in children. The indicators of MP-IgM positive rate in children vary greatly under different seasons and ages. Detection of MP-IgM positive rate and serum CRP level in children can provide reference for HSP diagnosis.

关 键 词：小儿过敏 紫癜 肺炎支原体 IGM阳性 C反应蛋白水平 

分 类 号：R725[医药卫生—儿科]