住院患者乙型肝炎表面抗原携带情况调查  

A study on the prevalence of hepatitis B surface antigen among inpatients

作　　者：杨丹丹 赵建荣 高丽 张红燕 彭干成 张恩俊 王舒 YANG Dan-dan;ZHAO Jian-rong;GAO Li;ZHANG Hong-yan;PENG Gan-cheng;ZHANG En-jun;WANG Shu(Internal Medicine/Intensive Care Unit (ICU),Yunnan Provincial Hospital of Infectious Diseases,Kunming 650301,China;Clinical Laboratory,Yunnan Provincial Hospital of Infectious Diseases;Infectious Diseases,Yunnan Provincial Hospital of Infectious Diseases;Medical Services,Yunnan Provincial Hospital of Infectious Diseases)

机构地区：[1]云南省传染病专科医院内科ICU,云南昆明650301 [2]云南省传染病专科医院检验科 [3]云南省传染病专科医院感染科 [4]云南省传染病专科医院医务科

出　　处：《中国病原生物学杂志》2018年第11期1265-1268,共4页Journal of Pathogen Biology

摘　　要：目的调查住院患者携带乙肝表面抗原情况。方法选取2014-2017年1 900例住院患者,抽取患者静脉血,采用ELISA检测试剂盒检测乙肝表面抗原携带情况,以及AIDS感染情况。结果 1 900例住院患者中乙肝表面抗原携带172例,携带率9.05%。2014-2017年各年度携带率分别为9.20%(46/500)、8.25%(33/400)、9.00%(36/400)和9.50%(57/600)。2014-2017年感染一科、感染二科、内科、外科、精神科片区患者携带率分别为12.75%、13.5%、8.13%、5.53%和2.92%。男性94例,女性78例,构成比分别为54.65%和45.35%。城市患者633例,乙肝表面抗原阳性56例,携带率8.85%,农村患者1 267例,阳性116例,携带率9.15%。公务员、教师、服务人员、农民及其他职业携带人数分别为37、19、53、56和7例,携带率分别为11.31%、6.21%、16.72.%、6.67%和6.31%。服务人员与公务员等其他职业患者相比,差异有统计学意义(χ^2=27.1628,P<0.05)。感染一科、感染二科、内科、外科、精神科片区住院患者乙肝表面抗原携带同时感染艾滋病患者数分别为54、17、21、51和1例,合并感染率分别为12.75%、13.5%、3.54%、5.53%和0.42%。结论住院患者乙肝表面抗原以感染科和服务人员为主,感染二科、感染一科、外科的艾滋病合并乙肝感染的居多,应引起重视。Objective To examine positivity for the hepatitis B surface antigen among inpatients in order to prevent the infection with the hepatitis B virus.Methods Clinical data on 1900 inpatients from 2014-2017 were examined,and venous blood was taken from the patients to detect the prevalence of hepatitis B surface antigen and AIDS using an ELISA test kit.The data were analyzed for significant differences.Results Of 1900 inpatients tested from 2014-2017,172 (9.05%)tested positive for hepatitis B surface antigen.Inpatients tested positive for hepatitis B surface antigen at a rate of 9.20% in 2014,8.25% in 2015,9.00% in 2016,and 9.50% in 2017.Fifty-four patients (31.40%) in Infectious Diseases No.1 tested positive for hepatitis B surface antigen,39(22.67%) in Infectious Diseases No.2 tested positive,21 (12.21%) in Internal Medicine tested positive,51(29.65%) in Surgery tested positive,and 7(4.07%) in Psychiatry tested positive.Of 172 inpatients who tested positive for hepatitis B surface antigen,94(54.65%) were male and 78 (45.35%) were female.Fifty-six inpatients (8.85%) who tested positive for hepatitis B surface antigen resided in an urban area,while 116(9.15%) who tested positive resided in a rural area.Of the inpatients who tested positive for hepatitis B surface antigen,37(11.31%) were civil servants,19(6.21%) were teachers,53(16.72%) worked in the service industry,56(6.67%) were farmers,and 7(6.31%) had some other profession.Fifty-four patients (12.75%) in Infectious Diseases No.1 tested positive for both hepatitis b surface antigen and AIDS,17(13.5%) in Internal Medicine tested positive for both,21(3.54%) in Surgery tested positive for both,51(5.53%) in Infectious Diseases No.2 tested positive for both,and 1(0.42%) in Psychiatry tested positive for both.Conclusion The prevalence of hepatitis B surface antigen in inpatients tended to decrease and then increase,and this was especially true in Infectious Diseases.The spread of vaccines has controlled the spread of hepatitis B to an extent,but new vaccines still need t

关 键 词：住院患者 乙型肝炎 表面抗原 携带情况 

分 类 号：R373.21[医药卫生—病原生物学]