稀土(La,Yb)-L-赖氨酸-5-氟尿嘧啶三元配合物的合成及其电化学活性研究  

Synthesis and Electrochemical Activity of Rare Earth( La,Yb)-L-Lys-5-Fu Ternary Complex

作　　者：陈华庆 王卫东 Chen Huaqing;Wang Weidong(Hubei Key Laboratory of Pollutant Analysis &Reuse Technology,College of Chemistry and Chemical Engineering,Hubei Normal University,Huangshi 435002,China)

机构地区：[1]污染物分析与资源化技术湖北省重点实验室,湖北师范大学化学化工学院,湖北黄石435002

出　　处：《中国稀土学报》2018年第6期692-699,共8页Journal of the Chinese Society of Rare Earths

基　　金：污染物分析与资源化技术湖北省重点实验室2015年开放基金项目(PA150209)资助.

摘　　要：在乙醇-水介质60℃水浴条件下合成了稀土(La,Yb)-L-赖氨酸-5-氟尿嘧啶三元配合物,利用滴定分析、元素分析、红外光谱、热重-差热等方法确定配合物的化学组成为:RE[(L-Lys)(5-Fu)Cl_3]·2H_2O (RE=La,Yb)。重点研究了配合物在铂盘电极上的电化学行为及其与牛血清白蛋白(BSA)的相互作用,发现配合物以HAc-NaAc缓冲溶液(pH≈6. 5)为底液,在设定电位范围(-0. 30～-0. 85 V)受扩散步骤控制,是准可逆的电化学行为。该配合物能够与牛血清白蛋白(BSA)发生相互作用,二者可能结合产生一种无电化学活性的物质。In ethanol-water medium (60℃),rare earth (La,Yb)-L-Lys-5-Fu ternary complexes were synthesized successfully.The general formula of the complexes were conformed to RE[(L-Lys)(5-Fu)Cl3]·2H2O by IR spectra,chemical analysis,elemental analysis and thermodynamic analysis.The electrochemical behavior of complexes was investigated by cyclic voltammetry.The results showed that RE^3+ was electrochemical active center in rare earth complex.Electrochemical behavior of complexes with BSA at a platinum working electrode was tested by cyclic voltammetry.The rare earth ternary complexes may react with BSA to produce an electrochemically non-active complex.

关 键 词：稀土 5-氟尿嘧啶 配合物 牛血清白蛋白 电化学 

分 类 号：O614.33[理学—无机化学]