慢性肾脏病3、4期中医证型与舌苔脱落细胞相关性分析  

Analysis of Relevance Between Syndrome Patterns of Traditional Chinese Medicine of Stage 3 and 4 of Chronic Kidney Disease and Exfoliated Cells of Tongue Coating

作　　者：莫超[1] 赵洁 孟立锋[2] 钱虹利 向长玉[1] 苏朝东 史伟[2] MO Chao;ZHAO Jie;MENG Lifeng;QIAN Hongli;XIANG Changyu;SU Chaodong;SHI Wei(Graduate School of Guangxi University of Chinese Medicine,Nanning 530001,Guangxi,China;Nephrology Department of The First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530023,Guangxi,China)

机构地区：[1]广西中医药大学研究生院,广西南宁530001 [2]广西中医药大学第一附属医院肾内科,广西南宁530023

出　　处：《中华中医药学刊》2018年第12期2885-2887,3095,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81560761);中国博士后科学基金项目(2017M612987);广西研究生教育创新计划项目(YJSP201711)

摘　　要：目的:探讨慢性肾脏病3、4期中医证型与舌苔脱落细胞分布规律,促进舌诊客观化。方法:选取慢性肾脏病3、4期患者80例,计算各个证型之间舌苔脱落细胞的成熟指数(MI)、成熟价值(MV),将各证型及20例正常人的结果进行比较分析。结果:脾肾阳虚证、脾肾气阴两虚证表层细胞所占比例、细胞成熟价值高于其他3组,中层细胞所占比例与此成负相关(P<0.01);湿浊证、湿热证表层细胞所占比例、细胞成熟价值高于其他4组,中层细胞所占比例与此成负相关(P<0.01);CKD4期、CKD3a期、CKD3b期、对照组之间的表层、中层的舌苔细胞所占比例、细胞成熟价值没有统计学差异(P>0.05)。结论:舌苔脱落细胞MI、MV分布规律与慢性肾脏病3、4期中医证型有关。Objective: To probe into the distribution regularity between the syndrome patterns of traditional Chinese medicine(TCM) of stage 3 and 4 of chronic kidney disease(CKD) and the exfoliated cells of tongue coatingin order to improve the objectification of tongue diagnosis. Methods: Eighty patients of CKD at stage 3 and 4 were selected. The maturity index(MI) and maturity value(MV) of the exfoliated cells of tongue coating of various syndrome patterns were calculated, and a comparative analysis was made between the results of various syndrome patterns and those of normal people. Result: Proportions and maturity value of superficial cells of patients with Yang deficiency of spleen and kidney and those with Qi and Yin deficiency of spleen and kidney were higher than those of other three groups and the proportion of intermediate cells was negatively correlated to this(P<0.01). The proportions and cell maturity value of superficial cells of patients with damp-turbidity syndrome and those with damp-heat syndrome were higher than those of other four groups and the proportion of intermediate cells was negatively correlated to this(P<0.01).The proportions and MV of superficial and intermediate tongue coating cells of CKD at stage 4,stage 3 a and stage 3 b and control group showed no statistical difference(P>0.05). Conclusion: The distribution regularity of MI and MV ofexfoliated cells of tongue coating is related to the TCM syndrome patterns of CKD at stage 3 and 4.

关 键 词：慢性肾脏病 舌苔脱落细胞 中医证型 相关性 

分 类 号：R692[医药卫生—泌尿科学]