氯硝柳胺乙醇胺盐不同剂型在江滩地区灭螺效果  被引量:3

Molluscicidal effects of different formulations of niclosamide ethanolamine salt in marshlands

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作  者:李伟[1] 游本荣 施亮 胡恒光 陈小俭 梅巧芳 杨坤[1] LI Wei;YOU Ben-rong;SHI Liang;HU Heng-guang;CHEN Xiao-jian;MEI Qiao-fang;YANG Kun(Key Laboratory of National Health Commission on Parasitic Disease Control and Prevention,Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology,Jiangsu Institute of Parasitic Diseases,Wuxi 214064,China;Luhe District Center for Diseases Control and Prevention,Nanjing City,Jiangsu Province,China)

机构地区:[1]国家卫生健康委员会寄生虫病预防与控制技术重点实验室、江苏省寄生虫与媒介控制技术重点实验室、江苏省血吸虫病防治研究所,无锡214064 [2]江苏省南京市六合区疾病预防控制中心

出  处:《中国血吸虫病防治杂志》2018年第5期540-543,共4页Chinese Journal of Schistosomiasis Control

基  金:江苏省卫生和计划生育委员会医学科研课题(X201505、ZDRCA2016056);江苏省预防医学科研课题(Y2015071);江苏省青年医学人才项目

摘  要:目的评价氯硝柳胺乙醇胺盐不同剂型在江滩地区的灭螺效果。方法选用25%氯硝柳胺乙醇胺盐悬浮剂(25%悬浮剂)、50%氯硝柳胺乙醇胺盐可湿性粉剂(50%可湿性粉剂)、4%氯硝柳胺乙醇胺盐粉剂(4%粉剂)等3种剂型灭螺药,在江滩有螺环境开展现场灭螺实验,比较不同剂型灭螺效果,并进行费用-效果分析。结果25%悬浮剂灭螺后3、7、15、30d钉螺校正死亡率和活螺密度下降率分别为54.37%、91.70%、92.76%、79.50%和59.55%、95.93%、97.63%、94.15%,4%粉剂分别为59.10%、91.83%、95.56%、93.34%和65.03%、94.93%、97.61%、97.28%,50%可湿性粉剂分别为76.29%、91.68%、93.12%、81.59%和81.24%、97.02%、97.84%、95.27%。25%悬浮剂、4%粉剂和50%可湿性粉剂的灭螺成本分别为0.21、0.39元/m^2和0.23元,m^2,钉螺校正死亡率每上升1%的平均费用分别为22.68、40.63元和25.17元,活螺密度每下降1%的平均费用分别为21.54、39.78元和23.95元。结论3种氯硝柳胺乙醇胺盐剂型现场灭螺效果均较好,均可用于江滩现场灭螺。但各药物起效时间、药效特点、现场喷施方法、灭螺成本等均有不同,应根据不同环境特点和使用条件合理选用。Objective To evaluate the molluscicidal effects of different formulations of niclosamide ethanolamine salt in marshlands.Methods The molluscicidal effects of spraying with 25% suspension concentrate of niclosamide ethanolamine salt (25% SCN)and 50% wettable powder formulation of niclosamide ethanolamine salt (50%WPN),and dusting with 4% niclosamide ethanolamine salt dustable powder (4%DP)for controlling Oncomelania hupensis snails were investigated and compared in the fields,and the cost-effectiveness was analyzed.Results The corrected mortalities and the reduced rates of density of snails were 54.37%,91.70%,92.76%,79.50%,and 59.55%,95.93%,97.63%,94.15%,respectively,on 3,7,15,30d after spaying with 25% SCN,those on 3,7,15,30d after dusting with 4% DP were 59.10%,91.83%,95.56%,93.34% and 65.03%,94.93%,97.61%,97.28%,respectively;and those on 3,7,15,30d after spraying with 50% WPN were 76.29%, 91.68%,93.12%,81.59%and 81.24%,97.02%,97.84%,95.27%,respectively.The cost of spraying with 25%SCN was 0.21 Yuan/m^2,that of dusting with 4% DP was 0.39 Yuan/m^2,and that of spraying with 50% WPN was 0.23 Yuan/m^2for snail control in the marshland.The cost of reduced one percentage of the corrected mortalities and the density of snails in controlling snails by 25% SCN,4% DP and 50% WPN on 15d were 22.68,40.63,25.17Yuan and 21.54,39.78,23.95 Yuan,respectively.Conclusions The three different formulations of niclosamide are reliable and effective for snail control in marshlands.There aresome differences among the different molluscicides in start time,pharmacodynamic characteristics,spraying methods in the field,cost of snail control,and influencing factors.Therefore,we need reasonably select the suitable molluscicides according to the environmental characteristics and working condition.

关 键 词:钉螺 25%氯硝柳胺乙醇胺盐悬浮剂 50%氯硝柳胺乙醇胺盐可湿性粉剂 4%氯硝柳胺乙醇胺盐粉剂 灭螺效果 费用-效果 江滩地区 

分 类 号:R383.24[医药卫生—医学寄生虫学]

 

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