十堰市妊娠期糖尿病孕产妇阴道微生态状况与妊娠结局的相关性  

Correlation between vaginal microecology and pregnancy outcome in pregnant women with gestational diabetes mellitus in Shiyan City

作　　者：陈清冉 李娟[1] 陈琳[1] 孟龙[1] CHEN Qing-Ran;LI Juan;CHEN Lin(Department of Obstetrics,Shiyan Maternal and Child Health Care Hospital,Shiyan,Hubei 442000,China)

机构地区：[1]十堰市妇幼保健院产科

出　　处：《中国妇幼保健》2018年第23期5356-5358,共3页Maternal and Child Health Care of China

基　　金：十堰市科学技术局(17Y75)

摘　　要：目的调查与分析十堰市妊娠期糖尿病孕产妇阴道微生态状况与妊娠结局的相关性。方法选取2016年2月-2017年6月在该院住院分娩的妊娠期糖尿病孕妇50作为观察组,同期选择在该院分娩的健康妊娠期妇女110例作为对照组,检测与记录两组的阴道微生态状况,调查妊娠结局并进行相关性分析。结果观察组孕妇的阴道微生态状况异常发生率为(70.0%)明显高于对照组(10.0%)(P<0.05)。观察组孕妇的早产、胎膜早破、绒毛膜羊膜炎、产褥感染等发生率明显多于对照组(P<0.05)。观察组围生儿的胎儿窘迫、新生儿感染、新生儿黄疸与低出生体质量儿等发生率明显高于对照组(P<0.05)。直线相关性分析显示,观察组孕妇的阴道微生态状况异常与早产、胎膜早破、绒毛膜羊膜炎产褥感染、胎儿窘迫、新生儿感染呈现明显正相关性(r=0.432、0.384、0.552、0.384、0.392、0.362,P<0.05)。结论十堰市妊娠期糖尿病孕产妇多表现为阴道微生态状况,可影响孕妇与围产儿的健康,且与妊娠结局明显相关。Objective To investigate and analyze the correlation between vaginal microecology and pregnancy outcome in pregnant women with gestational diabetes mellitus ( GDM) in Shiyan City.Methods From February 2016 to June 2017,50 pregnant women with GDM giving birth to their babies in Shiyan Maternal and Child Health Care Hospital were selected as observation group,and 110 healthy pregnant women giving birth to their babies in the hospital were selected as control group,vaginal microecology was detected and recorded,pregnancy outcome was surveyed,and the correlation was analyzed.Results The abnormal rate of vaginal microecology in observation group was 70.0%,which was statistically significantly higher than that in control group ( 10.0%) ( P<0.05) .The incidence rates of preterm labor,premature rupture of membranes,chorioamnionitis,and puerperal infection in observation group were statistically significantly higher than those in control group ( P<0.05) .The incidence rates of fetal distress,neonatal infection,neonatal jaundice,and low birth weight infants in observation group were statistically significantly higher than those in control group ( P<0.05) .Linear correlation analysis showed that abnormal vaginal microecology in observation group was significantly positively correlated with premature birth,premature rupture of membranes,chorioamnionitis,postpartum infection,fetal distress,and neonatal infection ( r = 0.432,0.384,0.552,0.384,0.392,0.362,P<0.05) .Conclusion Abnormal vaginal microecology is often observed in pregnant women with GDM in Shiyan City,which can affect the health of pregnant women and perinatal infants,and it is significantly related to pregnancy outcome.

关 键 词：十堰市 妊娠期糖尿病 阴道微生态 

分 类 号：R714.7[医药卫生—妇产科学]