金黄色葡萄球菌烫伤样皮肤综合征患者临床分析  

Clinical analysis of staphylococcal scalded skin syndrome caused by Staphylococcus aureus infection

作　　者：梅韬[1] 郭普[2] 韩洪方[1] 金慧玲[1] 江从军[1] MEI Tao;GUO Pu;HAN Hong-fang;JIN Hui-ling;JIANG Cong-jun(First Affiliated Hospital of Bengbu Medical College,Bengbu ,Anhui233004,China)

机构地区：[1]安徽省蚌埠医学院第一附属医院皮肤性病科,安徽蚌埠233004 [2]安徽省蚌埠医学院第一附属医院检验科,安徽蚌埠233004

出　　处：《中华医院感染学杂志》2018年第23期3580-3582,共3页Chinese Journal of Nosocomiology

基　　金：安徽省高等学校自然科学研究基金资助项目(KJ2015B011by)

摘　　要：目的探讨金黄色葡萄球菌感染引起的金黄色葡萄球菌烫伤样皮肤综合征(staphylococcal scalded skin syndrome,SSSS)患者的一般资料以及误诊和治疗转归情况。方法选择医院2014年10月-2017年10月收治的80例SSSS患儿临床资料进行分析,分析患儿的年龄分布、发病季节分布、误诊与治疗转归情况。结果 80例发病患儿,主要集中在幼儿期(1～3岁),32例占40.00%,其次为学龄前期(3～6岁),24例占30.00%;患儿发病时间主要为秋季,30例占37.50%,其次为夏季,20例占25.00%;76例被误诊为其他疾病,主要误诊为皮肤湿疹类过敏性疾病,20例占26.32%;所有患儿平均住院时间为(8.9±1.8)d,体温恢复正常平均时间为(1.8±0.9)d,尼氏征转阴平均时间为(3.9±1.7)d,2例患儿出现败血症、4例心肌损害,经治疗后好转。结论 SSSS发病年龄集中在婴幼儿和学龄前期,好发于秋季,在基层医院易被误诊,检查效果不佳,应早期应用足量敏感抗菌药物进行治疗。OBJECTIVE To investigate the general information,misdiagnosis and treatment outcomes of patients with staphylococcal scalded skin syndrome (SSSS)caused by Staphylococcus aureus infection.METHODS The clinical data of 80 children with SSSS admitted from Oct.2014to Oct.2017 were analyzed.The age distribution, seasonal distribution,misdiagnosis and treatment outcome of the patients were analyzed.RESULTS The 80 cases of children were mainly concentrated in early childhood (1-3 years old),with 32 cases accounting for 40.00%, followed by preschool (3-6 years old),with 24 cases accounting for 30.00%.The onset time was mainly autumn,with 30cases accounting for 37.50%,followed by summer,with 20cases accounting for 25.00%.76.cases were misdiagnosed as other diseases,mainly misdiagnosed as skin eczema-like allergic diseases,with 20 cases accounting for 26.32%.The average hospital stay time of all children was (8.9±1.8)d,the average time to recover to normal temperature was (1.8±0.9)d,and the mean duration of Nie's sign was (3.9±1.7)d.Two patients developed sepsis and 4 patients had myocardial damage,which were improved after treatment.CONCLUSION The age of SSSS onset is concentrated in infants and preschools.It often occurs in the fall and is easily misdiagnosed in primary hospitals.The examination results are not good.It should be treated with sufficient sensitive antibiotics at an early stage.

关 键 词：金黄色葡萄球菌 金黄色葡萄球菌烫伤样皮肤综合征 病原学 诊断 

分 类 号：R753[医药卫生—皮肤病学与性病学]