人参皂苷Rg_2、Rh_1对神经系统作用及相关机制的研究进展  

Advances on effects of ginsenoside Rg_2 and ginsenoside Rh_1 on nervous system and related mechanisms

作　　者：马赫佟 郜玉钢[1] 祝洪艳[1] 赵岩[1] 杨鹤[1] 刘双利[1] 张连学[1] 何忠梅[1] MA Hetong;GAO Yugang;ZHU Hongyan;ZHAO Yan;YANG He;LIU Shuangli;ZHANG Lianxue;HE Zhongmei(College of Chinese Medicinal Materials,Jilin Agricultural University,Changchun 130118,China)

机构地区：[1]吉林农业大学中药材学院,吉林长春130118

出　　处：《上海中医药杂志》2018年第12期110-112,共3页Shanghai Journal of Traditional Chinese Medicine

基　　金：吉林省科技厅科技计划发展项目(20180414072GH)

摘　　要：通过检索人参皂苷Rg_2和Rh_1神经系统药理研究文献,综述人参皂苷Rg_2和Rh_1在此方面的药理作用及其相关作用机制的研究进展。现代药理学研究显示,人参皂苷Rg2和Rh1在神经系统方面具有很强的药理活性,具有保护神经细胞、抗脑缺血再灌注损伤、治疗阿尔茨海默病及血管性痴呆、抗抑郁等作用。By searching for the literatures on neuropharmacology of ginsenosides Rg2 and Rh1 ,the related pharmacological effects and mechanisms of ginsenosides Rg2 and Rh1 are reviewed. Modern pharmacological studies have found that ginsenosides Rg2 and Rh1 show strong pharmacological activity in nervous system,which can protect nerve cells,anti cerebral ischemia-reperfusion injury,treat Alzheimer’s disease and vascular dementia,anti-depression and so on.

关 键 词：人参皂苷RG2 人参皂苷RH1 神经系统 药理作用 作用机制 综述 

分 类 号：R285.5[医药卫生—中药学]