双水相法回收可利霉素生产废水中的螺旋霉素  

Recovery of Spiramycin from Kelimycin Production Wastewater by Aqueous Two-phase Extraction

作　　者：周梦飞 陈葵[1] 朱家文[1] 武斌[1] 吴艳阳[1] 纪利俊[1] ZHOU Meng-fei;CHEN Kui;ZHU Jia-wen;WU Bin;WU Yan-yang;JI Li-jun(School of Chemical Engineering,East China University of Science and Technology,Shanghai 200237,China)

机构地区：[1]华东理工大学化工学院

出　　处：《精细化工》2018年第12期2127-2131,2160,共6页Fine Chemicals

摘　　要：采用浊点滴定法测定了乙醇-K2HPO4双水相体系的双节线相图,并使用经验方程对数据进行拟合,建立了乙醇-K2HPO4双水相体系萃取螺旋霉素的方法,系统考察了K2HPO4质量分数、乙醇质量分数、螺旋霉素初始浓度、萃取温度和体系pH对分配系数和萃取率的影响。结果表明:双水相萃取螺旋霉素是自发进行、吸热熵增的过程。当K2HPO4质量分数为总体系的20%、乙醇质量分数为总体系的16%、萃取温度为25℃、体系pH=9.5时,分配系数达到47.52,萃取率达到97.97%。Binodal curve of ethanol-K2 HPO4 aqueous two-phase system(ATPS) was measured by the turbidimetric titration method. Empirical equations were used to correlate the bimodal curves. A method for separation of spiramycin by ethanol-K2 HPO4 aqueous two-phase system extraction was established. Parameters affecting the partition coefficient and extraction efficiency such as mass fraction of K2 HPO4, mass fraction of ethanol, initial concentration of spiramycin, extraction temperature and pH of the system were investigated. The results demonstrated that the extraction of spiramycin was a spontaneous, endothermic and entropy increasing process. When the K2 HPO4 mass fraction was 20% of the total system, the ethanol mass fraction was 16% of the total system, the extraction temperature was 25 ℃, and the pH of the system was 9.5, the partition coefficient and extraction efficiency of spiramycin reached 47.52 and 97.97%, respectively.

关 键 词：螺旋霉素 双水相萃取 乙醇 磷酸氢二钾 热力学 水处理技术 

分 类 号：TQ028[化学工程]