超声弹性成像评估2型糖尿病患者胫神经病变的应用价值  

Assessment of Tibial Neuropathy by Using Sonoelastography in Type 2 Diabetes Mellitus

作　　者：滕飞 周显礼[1] 薛伟力[1] 董雪迎[1] 马饶 Teng Fei;Zhou Xianli;Xue Weili(Department of Ultrasound,The Second Affiliated Hospital,Harbin Medical University,Heilongjiang 150086,China)

机构地区：[1]哈尔滨医科大学附属第二医院住院处超声科,150086

出　　处：《医学研究杂志》2018年第11期163-167,共5页Journal of Medical Research

摘　　要：目的探讨超声弹性成像评估2型糖尿病患者胫神经病变的应用价值。方法对2型糖尿病伴周围神经病变患者33例、不伴周围神经病变患者32例及29例健康志愿者胫神经应用常规高频超声测量前后径及横截面积(cross-sectional area,CSA),应用声触诊组织定量(virtual touch tissue quantification,VTQ)技术及声触诊组织成像和定量(virtual touch tissue imaging quantification,VTIQ)技术测量剪切波速度(sheer wave velocity,SWV),对比分析VTQ及VTIQ两种弹性成像技术对2型糖尿病患者胫神经病变的应用价值。结果 2型糖尿病伴周围神经病变者胫神经前后径、CSA、SWV值均大于不伴周围神经病变者,且大于健康志愿者(P <0. 05)。VTIQ技术诊断2型糖尿病周围神经病变的敏感度及特异性高于VTQ技术(P <0. 05)。结论 2型糖尿病患者出现周围神经病变之前,胫神经硬度已发生变化,VTQ及VTIQ技术均可较早发现这一变化。VTIQ技术对2型糖尿病患者胫神经病变诊断价值优于VTQ技术。Objective Sonoelastography in the evaluation of tibial neuropathy in patients with type 2 diabetes mellitus.Methods The anterior -posterior diameter and cross -sectional area (CSA)of the tibial nerve were measured by high -frequency uhrasonnd.The SWV of the tibial nerve was measured by virtual touch tissue quantification(VTQ)and virtual touch tissue imaging quantification(VTIQ) in thirty-three patients of type 2 diabetes mellitus with diabetic periphreal neuropathy,thirty-two patients of type 2 diabetes mellitus without diabetic periphreal neuropathy and twenty -nine healthy volunteers.We compared and analyzed the value of VTQ and VTIQ technique in the changes of tibial nerve hardness in type 2 diabetes mellitus.Results The anterior-posterior diameter,CSA,SWV of the tibial nerve in type 2diabetes mellitus with DPN group were higher than the type 2 diabetes mellitus without DPN group,and higher than the healthy volunteers (P<0.05).The sensitivity and specificity of VTIQ technique were higher than VTQ technique in the diagnosis of tibial neuropathy in type 2 diabetes mellitus (P<0.05).Conclusion The hardness of the tibial nerve in type 2 diabetes mellitus has changed before the onset of DPN.Both VTQ and VTIQ technique ean deteet this change earlier.VTIQ is superior to VTQ technique in the diagnosis of tibial neuropathy in type 2 diabetes mellitus.

关 键 词：超声弹性成像 2型糖尿病 糖尿病周围神经病变 胫神经 

分 类 号：R4[医药卫生—临床医学]