2型糖尿病住院患者握力水平及相关因素分析  

Analysis on hand grip strength and its relative factors among 166 inpatients with type 2 diabetes mellitus

作　　者：葛智文[1] 洪忠新[1] 张立红[1] 毕研霞[1] 李伟[1] 王楠 屈卫华[1] Ge Zhiwen;Hong Zhongxin;Zhang Lihong;Bi Yanxia;Li Wei;Wang Nan;Qu Weihua(Department of Nutrition,Belting Friendship Hospital,Capital Medical University ,Beijing100050,China)

机构地区：[1]首都医科大学附属北京友谊医院营养科,北京100050

出　　处：《中国临床保健杂志》2018年第6期776-781,共6页Chinese Journal of Clinical Healthcare

摘　　要：目的探讨2型糖尿病患者握力水平及其相关因素。方法选取166例2型糖尿病患者作为糖尿病组;选取同时期住院的510例非2型糖尿病,但有肥胖、血脂异常、高血压等代谢综合征危险指征的疾病患者作为非糖尿病组对照。入院后48 h内收集身高、体质量、体质指数、腰围、臀围、总蛋白、清蛋白、肌酐、尿素氮、血压、血糖、胰岛素、握力等指标,并计算胰岛素抵抗指数、营养风险指数等。结果无论男性还是女性,在糖尿病组与非糖尿病组的年龄、体质指数、腰围、臀围、有无吸烟或饮酒、是否合并肥胖、血脂异常、高血压等疾病等方面均差异无统计学意义的情况下,糖尿病组患者的握力低于非糖尿病组,胰岛素抵抗的比例高于非糖尿病组(P <0.05)。相关分析结果显示无论男性还是女性,糖尿病患者的握力与其体质指数、腰围、清蛋白、总蛋白、肌酐、营养风险指数呈正相关(P <0.05),与年龄、糖尿病病程、糖尿病并发症数量、其他代谢性疾病数量、空腹血糖、餐后2 h血糖、胰岛素抵抗指数呈负相关(P <0.05)。多元线性回归分析结果显示,年龄、性别、体质指数、糖尿病病程长短、糖尿病并发症数量、合并其他代谢性疾病数量、清蛋白、总蛋白、肌酐可能影响糖尿病患者的握力(P <0.05)。结论糖尿病患者的握力下降,其与糖尿病病程、并发症、相关代谢性疾病及机体蛋白质储备情况有关。Objective To investigate the hand grip strength and its relative factors in hospitalized patients with type 2 diabetes mellitus. Methods According to the inclusive and exclusive criteria,166 inpatients with type 2 diabetes mellitus were enrolled as the diabetic group,while 510 non-diabetes inpatients with metabolic syndrome related diseases like obesity,dyslipidemia,and hypertension,were enrolled as the non-diabetic group.Dominant hand grip strength (HGS),height,weight,body mass index (BMI),waist circumference (WC),hip circumference (HC),serum total protein (TP),albumin (ALB),creatinine (Cr),urea nitrogen (BUN),blood pressure,blood glucose,and plasma insulin of patients were measured within 48 hours after admission,and resistance index and nutrition risk index (NRI) were calculated. Results For both men and women,there were no statistically significant difference in age,BMI,WC,HC,lifestyle habits (including smoking and drinking),proportions of obesity,dyslipidemia and hypertension between diabetic group and non-diabetic group,the hand grip strength of diabetic patients were lower than those in non-diabetic group,and the proportion of insulin resistance was higher than that in the non-diabetic group (P<0.05).Results The dominant hand grip strength was positively correlated with BMI,WC,TP,ALB,Cr,NRI (P<0.05),and negatively correlated with age,length of course,numbers of diabetes complications,other metabolic diseases,plasma glucose of fasting,plasma glucose of 2 hours after meal,and insulin resistance index (P<0.05) regardless of male of female.Multiple linear regression showed that age,sex,BMI,length of course,numbers of diabetes complications and other metabolic diseases,TP,ALB,Cr might affect the HGS of diabetic patients (P<0.05). Conclusion The hand grip strength of patients with diabetes mellitus is reduced,which is related to the diabetic course,numbers of complications,other metabolic diseases and the reservation of protein.

关 键 词：糖尿病 2型 手部肌力 诊断技术和方法 营养状况 

分 类 号：R587.1[医药卫生—内分泌]