前列腺增生合并糖尿病患者下尿路症状特点尿动力学分析  

Urodynamics in diabetic patients complicated with benign prostatic hyperplasia

作　　者：刘亚东[1] 卢晓明[1] 周国洋[1] 王进峰[1] 尹九湖[1] 王礼平[1] 董彬彬[1] 卫中庆[2] Liu Yadong;Lu Xiaoming;Zhou Guoyang;Wang Jinfeng;Yin Jiuhu;Wang Liping;Dong Binbin;Wei Zhongqing(Department of Urology,Yancheng Third People′s Hospital,Yancheng 224000,China;Department of Urology,the Second Affiliated Hospital to Nanjing Medical University,Nanjing 210011,China)

机构地区：[1]江苏省盐城市第三人民医院泌尿外科,224000 [2]南京医科大学第二附属医院泌尿外科,210011

出　　处：《中华全科医师杂志》2018年第12期1006-1008,共3页Chinese Journal of General Practitioners

摘　　要：回顾性分析盐城市第三人民医院2014年1月至2017年7月收治的30例良性前列腺增生(BPH)合并糖尿病(DM)患者(BPH+DM组)、37例单纯BPH患者(BPH组)的尿动力学检查资料。BPH+DM和BPH组在膀胱排出梗阻指数(BOOI)-膀胱收缩指数(BCI)拟合曲线上、下者分别为22(A组)和15例(B组)、14(C组)和16例(D组);膀胱初感觉容量、最大膀胱容量、最大逼尿肌压力、BOOI、BCI分别是(300.5±118.4)和(172.7±93.0)ml、(509.3±98.6)和(311.9±147.1)ml、(49.7±32.9)和(84.7±51.5)cmH2O(1cmH2O=0.098kPa)、35.9±32.3和69.7±53.7、84.2±43.3和122.3±50.2,差异均有统计学意义(均P<0.05),残余尿量为41.5ml(0~450ml)和10.0ml(0~200ml)。BPH组和BPH+DM组的BOOI-BCI拟合曲线相关系数分别为0.889和0.724。A组和B组的手术前后国际前列腺症状评分差值[IPSS(术前-术后)]、最大尿流率差值[Qmax(术前-术后)]分别是7.6±3.5和7.3±4.1、(2.6±1.1)和(3.7±1.3)ml/s,C组和D组的IPSS(术前-术后)、Qmax(术前-术后)分别是5.3±2.4和6.0±3.3、(2.4±1.0)和(3.8±1.4)ml/s,A组和B组、C组和D组Qmax(术前-术后)比较差异均有统计学意义,而IPSS(术前-术后)差异均无统计学。BOOI-BCI线性曲线下组患者较曲线上组患者有更好的手术受益。The clinical and urodynamic data of 37 patients with benign prostate hyperplasia(BPH) and 30 diabetic patients complicated with BPH (BPH+DM) admitted between Jan 2014 and July 2017were analyzed retrospectively. The International Prostate Symptom Score (IPSS), maximal flow rate (Q max ),post-voiding residual urine volume (PVR), maximum cystometric capacity (MCC), first desire to void (FDV),pressure of detrusor maximum (P det, max ), bladder outlet obstruction index (BOOI), bladder contraction index(BCI) were compared between BPH group and BPH+DM group. According to BOOI-BCI linear regression,22 cases (group A) and 15 cases (group B) of BPH patients were above and below the linear curve; whilethere were 14 cases (group C) and 16 cases(group D)of BPH+DM patients above and below the curve,respectively. The mean±SD FDV, MCC, P det, max , PVR, BOOI, BCI were (172.7±93.0)ml vs. (300.5±118.4)ml(P<0.05), (311.9±147.1)ml vs. (509.3±98.6)ml (P<0.05), (84.7±51.5)cmH 2 O(1 cm H 2 O=0.098 kPa) vs. (49.7±32.9)cmH 2 O vs (P<0.05), 10.0 ml(0-200 ml) vs. 41.5 ml(0-450 ml), 69.7±53.7 vs. 35.9±32.3 (P<0.05),122.3±50.2 vs 84.2±43.3 (P<0.05) in BPH and BPH+DM groups, respectively. In BPH group and BPH+DMgroup, the regression coefficients of BOOI-BCI were 0.889 and 0.724, respectively. In group A and group B,the difference value of IPSS and Q max pre and post operation were 7.6±3.5 and 7.3±4.1 (P>0.05), (2.6±1.1)ml/sand (3.7±1.3) ml/s (P<0.05), respectively. In group C and group D, the difference value of IPSS and Q max preand post operation were 5.3±2.4 and 6.0±3.3 (P>0.0 5), (2.4±1.0)ml/s and (3.8±1.4)ml/s (P<0.05),respectively. The study indicates that the therapeutic effect is better for the patients blow BOOI - BCIregression linear curve compared to the patients above the linear curve.

关 键 词：前列腺增生 糖尿病 尿动力学 诊断 

分 类 号：R697.3[医药卫生—泌尿科学] R587.2[医药卫生—外科学]