补肾养卵方合督脉灸治疗卵泡发育不良临床观察  被引量:5

Clinical Observation of Bushen Yangluan Prescription Combined with Moxibustion on Du Meridian for Follicular Dysplasia

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作  者:何田田[1] 邓雪梅[1] 谢璐[1] 陈凤媚[1] HE Tiantian;DENG Xuemei;XIE Lu;CHEN Fengmei

机构地区:[1]广东省妇幼保健院中医科,广东广州510010

出  处:《新中医》2018年第12期224-227,共4页New Chinese Medicine

基  金:陈凤媚名中医传承工作室项目(广东省中医药管理局2018年省名中医传承工作室建设项目;2015年广东省强省专项广东省首批名中医师承项目)

摘  要:目的:观察补肾养卵方联合督脉灸治疗卵泡发育不良的临床疗效。方法:将卵泡发育不良而导致不孕的患者50例随机分为2组各25例,于卵泡生长期分别采用不同治疗,治疗组予以督脉灸治疗和陈凤媚经验方补肾养卵方内服,西药组予以克罗米芬(CC)联合绒促性素(HCG)的促排卵方案,连续治疗3个月经周期,观察2组的卵泡生长情况、子宫内膜厚度及形态变化、排卵率、妊娠率。结果:治疗组25例,于治疗第2个周期成功妊娠1例,第3个周期成功妊娠4例,共完成69个月经周期;西药组25例,于治疗第1个周期妊娠4例(其中胚胎停育1例),第2个周期成功妊娠2例,第3个周期成功妊娠1例,共完成65个月经周期。治疗组排卵率为84.1%,西药组的排卵率为70.8%,2组比较,差异有统计学意义(P <0.05)。治疗组妊娠率为20.0%,西药组妊娠率为24.0%,2组比较,差异无统计学意义(P> 0.05)。在2组有排卵的周期中,2组卵泡平均直径均较治疗前有升高,治疗前后卵泡平均直径比较,差异均有统计学意义(P <0.05);治疗后,治疗组与西药组有排卵周期卵泡平均直径比较,差异无统计学意义(P> 0.05)。治疗组围排卵期的子宫内膜厚度高于西药组,差异有统计学意义(P <0.05);明显三线征A型内膜的比例治疗组为72.5%,西药组为46.2%,差异有统计学意义(P <0.05)。结论:补肾养卵方和督脉灸联合使用,能调补肾之阴阳,促使卵泡发育,提高成熟卵泡排卵率,并能避免西药治疗中卵泡与子宫内膜生长不同步。Objective:To observe the clinical effect of Bushen Yangluan prescription combined with moxibustion on Du meridian for follicular dysplasia. Methods:Divided 50 patients with infertility caused by follicular dysplasia into two groups randomly,25 cases in each group. Applied different treatment in the follicular growth phase: the treatment group was treated with moxibustion on Du meridian and the oral administration of the Bushen Yangluan prescription of Chen Fengmei’s experienced prescription, while the western medicine group was given clomiphene(CC) combined with human chorionic gonadotropin (HCG) for ovulation induction. The treatment for both groups lasted for 3 menstrual cycles. Observed follicular growth,endometrial thickness and morphological changes, ovulation rate and pregnancy rate in the two groups. Results:There was 1 case of successful pregnancy in the second cycle of the treatment and 4 cases in the third cycle among the 25 cases in the treatment group,and 69 menstrual cycles were completed in total. There was 4 cases of successful pregnancy (including 1 case of embryo damage ) in the first cycle of the treatment, 2 cases in the second cycle and 1 case in the third cycle among the 25 cases in the western medicine group,and 65 menstrual cycles were completed in total. The ovulation rate was 84.1% in the treatment group and 70.8% in the western medicine group,compared the two groups, difference being significant(P<0.05). The pregnancy rate was 20.0% in the treatment group and 24.0% in the western medicine group, compared the two groups,there was no significance in the difference(P>0.05). In the cycles where the ovulation appeared in the two groups,the average diameters of follicle in the two groups were increased when compared with those before treatment,compared the average diameters of follicle before and after treatment,differences being significant(P<0.05). After treatment,there was no significant difference being found in the comparison of the average diameters of follicle during the cycles in whi

关 键 词:卵泡发育不良 补肾养卵方 督脉灸 名医经验 克罗米芬(CC) 绒促性素(HCG) 

分 类 号:R711.75[医药卫生—妇产科学]

 

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