缺血性心肌病的多模态心血管影像学方法进展  

Progress in Multimodal Cardiovascular Imaging of Ischemic Crdiomyopathy

作　　者：杨丽萍 王可铮 曹绍东[2] 高超[2] YANG Li-ping;WANG Ke-zheng;CAO Shao-dong;GAO Chao(PET-CT/MR Center, Harbin Medical University Affiliated Cancer Hospital, Harbin, Heilongjiang,150086, China;Department of Medical Imaging, Fourth Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang,150001, China)

机构地区：[1]哈尔滨医科大学附属肿瘤医院PET-CT/MR中心,黑龙江哈尔滨150086 [2]哈尔滨医科大学附属第四医院医学影像科,黑龙江哈尔滨150001

出　　处：《现代生物医学进展》2018年第21期4173-4176,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金面上项目(81571740);国家自然科学基金青年项目(81101086);黑龙江省自然科学基金留学归国人员科学基金项目(LC201436);黑龙江省博士后启动基金项目(2017)

摘　　要：近年来,超声(ultrasound, US)、CT冠状动脉造影(CT coronary angiography, CCTA)、血管内超声(intravenous ultrasound,IVUS)、光学相干断层成像(optical coherence tomography, OCT)、多层螺旋CT成像(multi-slice computed tomography, MSCT)、单光子发射计算机断层成像(single-photon emission computed tomography, SPECT)、正电子发射计算机断层成像(positron emission computed tomography, PET)及心脏磁共振(cardiac magnetic resonance, CMR)等多种心血管成像技术能够提供与冠脉病变及心肌形态和功能相关的解剖学、血流动力学、细胞生物学及病理生理学等方面的重要信息,在缺血性心肌病的临床诊疗及预后评估中发挥着日益重要的作用。然而,如何恰当选择的多模态心血管影像技术是临床医师面临的一大难题。因此,本文在归纳总结主要心血管成像技术临床应用进展的基础上,对多模态心血管影像学在缺血性心肌病相关的冠脉解剖与斑块成像、心肌功能、心肌灌注及心肌活性显像中的临床应用价值进行综述。旨在帮助临床医师客观认识各种成像技术的优势与不足,从而制定最优化的选择方案。In recent years, ultrasound (US), CT coronary angiography (CCTA), intravascular ultrasound (IVUS), optical coherence tomography (OCT), multi-slice spiral CT (MSCT), single photon emission computed tomography (SPECT). Positron emission tomography (PET) and cardiac magnetic resonance (CMR) and other cardiovascular imaging techniques can provide important informationon anatomy, hemodynamics, cytobiology and pathophysiology. It is playing an increasingly important role in the diagnosis, treatment andprognosis evaluation of ischemic cardiomyopathy. However, how to properly select multimodal cardiovascular imaging techniques is amajor problem for clinicians. Therefore, on the basis of summarizing the clinical application of major cardiovascular imaging techniques,the clinical value of multimodal cardiovascular imaging in coronary artery anatomy and plaque imaging, myocardial function, myocardialperfusion and myocardial viability is reviewed. It aims to help clinicians to objectively understand the advantages and disadvantages ofvarious imaging techniques so as to make optimal choices.

关 键 词：缺血性心肌病 心肌功能 心肌灌注 心肌活性 多模态 

分 类 号：R541.1[医药卫生—心血管疾病] R445[医药卫生—内科学]