子宫内膜异位症患者腹腔镜术后生殖预后的影响因素分析  

Clinical factors of reproductive outcome after laparoscopic treatment in patients with endometriosis

作　　者：焦海宁[1] 朱岚[1] 吴步初[1] 冯炜炜 Jiao Haining;Zhu Lan;Wu Buchu;Feng Weiwei(Department of Gynecology and Obstetrics, Ruijin Hospital of Shanghai Jiaotong University, Shanghai 200025, China)

机构地区：[1]上海交通大学医学院附属瑞金医院妇产科,200025

出　　处：《中国医师杂志》2018年第12期1807-1809,1813,共4页Journal of Chinese Physician

摘　　要：目的探讨影响子宫内膜异位症(内异症)不孕患者腹腔镜术后生殖预后的影响因素。方法回顾性分析2010年1月至2017年1月本院收治的80例子宫内膜异位症合并不孕症患者腹腔镜术后的妊娠情况,并对相关因素进行logistic回归分析。结果 80例患者最终术后妊娠率为37. 5%(30/80),研究显示有8例> 12个月妊娠,22例≤12个月妊娠。另外合并术后规范用药[促性腺激素释放激素类药物(GnRH-a)](OR=19. 222,95%CI:3. 528～104. 731,P <0. 05)及术后接受辅助生育技术(OR=13. 581,95%CI:1. 913～96. 397,P <0. 05)与患者术后妊娠率具有相关性。结论术后规范用药(GnRH-a)及接受辅助生育技术是子宫内膜异位症合并不孕症患者腹腔镜术后生殖预后的重要影响因素。Objective To investigate the factors correlated to the pregnancy rate of the patients with endometriosis after laparoscopy. Methods A total of 80 patients with endometriosis related infertile who received laparoscopic surgery in our hospital from January 2010 to January 2017 were enrolled in this study. The postoperative pregnancy of the patients and related factors were analyzed by logistic regression. Results The postoperative pregnancy rate was 37.5% (30/80). Among the pregnancies, 22 cases were ≤12 months, 8 cases >12 months.Logistic regression analysis revealed that postoperative combined medication [gonadotropin-releasing hormone-agonist (GnRH-a)] (OR=19.222, 95% CI: 3.528-104.731, P<0.05) and artificial proconceptive (OR=13.581, 95% CI: 1.913-96.397, P<0.05) are correlated with pregnancy rate after laparoscopic surgery. Conclusions Postoperative combined medication and artificial proconceptive are influencing factors of pregnancy rate after laparoscopy in endometriosis patients with infertile.

关 键 词：子宫内膜异位症/并发症/外科学 不育 女(雌)性/病因学/外科学 腹腔镜检查 妊娠率 

分 类 号：R713.4[医药卫生—妇产科学]