袖状胃切除术对反复发作肥胖型急性高脂血症性胰腺炎的疗效  

The impact of sleeve gastrectomy on recurrent obese hyperlipidemic pancreatitis

作　　者：吴国刚[1] 王明辉[1] 沈静 刘兆润[1] 冷梅[1] 刘吉盛[1] 富民[1] Wu Guogang;WangMinghui;Shen Jing;Liu Zhaorun;Leng Mei;Liu Jisheng;Fu Min(Department of General Surgery,Anshan Iron and Steel Group General Hospital,AnShan 114002,Liaoning Province,China)

机构地区：[1]鞍钢集团总医院普通外科,辽宁鞍山114002

出　　处：《中华肝胆外科杂志》2018年第12期829-832,共4页Chinese Journal of Hepatobiliary Surgery

摘　　要：目的观察减重手术对肥胖型急性高脂血症性胰腺炎(HLAP)反复发作的治疗效果。方法选择鞍钢集团总医院普通外科收治的10例反复发作肥胖型HLAP病情稳定3个月后的患者为研究对象,所有患者均行腹腔镜袖状胃切除术(LSG)治疗,并于术后1…3612、24个月进行随访,监测患者体重、BMI、多余体重减除率(EWL)、血液指标(TG、LDL—C、HDL—C、TC、FPG、HbAlc、UA、hs.ClIP、ESR、血流变)变化,观察术后HLAP复发及合并症改善情况。结果LSG后10例肥胖型HLAP患者体重、BMI、EWL及血液指标均随着随访时间的推移逐渐下降,与术前比较差异有统计学意义(P<0.05)。术后12个月上述观察指标趋于平稳,随访24个月HLAP无反复。结论LSG可以减轻患者体重,改善患者的代谢状态,从源头上阻断肥胖型HLAP的发生,可以作为肥胖型HLAP病情稳定后的有效干预措施。Objective To study the impact of weight loss surgery after 3months of stable condition through intervention on patients with obese hyperlipidemic acute pancreatitis (HLAP).Methods Ten patients with obese HLAP who underwent laparoscopic sleeve gastrectomy (LSG)at the General Surgery Department of our hospital were followed-up at 1,3,6,12,24months after surgery.Their weight,BMI, EWL,and blood parameters (TG,LDL-C,HDL-C,TC,FPG,HbAlc,UA,hs-CRP,ESR,and hemorheology indexes)were compared.The impact on postoperative obese HLAP was assessed.Results The weight,BMI,EWL and blood index (TG,LDL-C,HDL-C,TC,FPG,HbAlc,UA,hs-CRP,ESR,and hemorheology indexes)of the patients gradually decreased.The decrease was significantly different from that before surgery (P<0.05),which became stable at 12months and with no recurrence at 24months after surgery.Conclusions LSG reduced body weight and improved metabolic status of the patients.It stopped the occurrence of obese HLAP.LSG can be used as an effective intervention for patients with obese HLAP.

关 键 词：急性高脂血症性胰腺炎 肥胖 袖状胃切除术 

分 类 号：R656.61[医药卫生—外科学]