长沙市HIV感染者/AIDS病人对随访管理及治疗服务依从性调查  

Follow-up management and adherence to antiretroviral therapy among people living with HIV/AIDS in Changsha City

作　　者：余阳 彭碧华 黄竹林[3] 陈曦[4] 王敏 罗丹[1] YU Yang;PENG Bi-hua;HUANG Zhu-lin;CHEN Xi;WANG Min;LUO Dan(Xiangya School of Public Health, Central South University, Changsha, Hunan 410078, China;Xiangya Hospital, Central South University, Changsha, Hunan 410008, China;Changsha Municipal Center for Disease Control and Prevention, Changsha, Hunan 410004, China;Hunan Provincial Center for Disease Control and Prevention, Changsha, Hunan 410005, China;Institute for AIDS, the First Hospital of Changsha City, Changsha, Hunan 430100, China)

机构地区：[1]中南大学湘雅公共卫生学院,湖南长沙410078 [2]中南大学湘雅医院,湖南长沙410008 [3]长沙市疾病预防控制中心,湖南长沙410004 [4]湖南省疾病预防控制中心,湖南长沙410005 [5]长沙市第一医院艾滋病研究所,湖南长沙430100

出　　处：《实用预防医学》2019年第1期22-25,共4页Practical Preventive Medicine

基　　金：湖南省社会科学基金(13WTB22);国家自然科学基金(81202290)

摘　　要：目的 了解HIV感染者/AIDS病人对随访管理及治疗服务的依从现状并探讨其相关因素。 方法 以长沙市疾病预防控制中心和艾滋病定点治疗医院为调查现场,将在2013年3月1日-2015年8月31日期间开始接受抗病毒治疗的HIV感染者/AIDS病人(治疗时长为3~6个月)作为连续样本征募入组,获得有效样本207例。采用“美国社区艾滋病临床研究抗逆转录病毒用药自陈式问卷”及自编的一般情况问卷进行调查;CD4检测和常规随访数据来源于艾滋病综合防治信息系统。 结果 样本对随访管理的依从率为96.6%,抗病毒治疗服药量依从率为87.0%;随访管理及治疗服务依从率为75.4%。多因素分析显示,有稳定工作(OR=2.30,95%CI:1.06~4.98)、治疗方案为“其他组合”(OR=5.49,95%CI:2.15~14.02)的样本依从更差。 结论 长沙市HIV感染者/AIDS病人对随访管理服务的依从性较好,但其服药依从性有待提高。在管理及治疗服务中,应及时为该人群提供服药指导及心理支持。Objective To investigate the current status and related factors of follow-up management and adherence to antiretroviral therapy among HIV-infected/AIDS patients in Changsha City. Methods HIV-infected/AIDS patients who received antiretroviral therapy between March 1, 2013 and August 31, 2015 (the duration of treatment was 3-6 months) were selectedfrom Changsha Municipal Center for Disease Control and Prevention and HIV/AIDS designated hospitals in Changsha City to serve as continuous study subjects, and a total of 207 participants were enrolled. Community Programs for Clinical Research on AIDS Antiretroviral Medication Self-Report Questionnaire and the General Information Questionnaire were used to assess the levels of medication adherence. The data regarding CD4 detection Results and regular follow-up were extracted from the Comprehensive AIDS Prevention and Control Information System. Results Among the 207 participants, the rates of adherence to follow-up management, dosage of antiretroviral medication and follow-up management & medication were 96.6%, 87.0% and 75.4% respectively. Multivariate logistic analysis showed that patients with stable job (OR=2.30, 95%CI:1.06-4.98) and patients with combined therapeutic regimens (OR=5.49, 95%CI:2.15-14.02) had poor adherence. Conclusions The adherence to follow-up management in HIV-infected/AIDS patients in Changsha City is good, but their medication compliance needs to be improved; and hence, it is necessary to timely provide medication guidance and psychological support among them.

关 键 词：HIV感染者/AIDS病人 抗病毒治疗 依从性 影响因素 

分 类 号：R512.91[医药卫生—内科学]