2012-2017年德阳市早产儿支气管肺发育不良流行病学特征分析  

The Epidemiological Characteristics of Bronchopulmonary Dysplasia in Premature Infants in Deyang From 2012 to 2017

作　　者：邓全敏[1] 黄琴[1] 李雪梅[1] DENG Quanmin;HUANG Qin;LI Xuemei(Deyang People's Hospital,Deyang 618000,Sichuan Province,China.)

机构地区：[1]德阳市人民医院

出　　处：《预防医学情报杂志》2019年第1期51-54,共4页Journal of Preventive Medicine Information

摘　　要：目的对2012-2017年四川省德阳市早产儿支气管肺发育不良(bronchopulmonarydysplasis,BPD)进行流行病学特征分析,为该病预防提供策略。方法回顾性调查2012-2017年德阳市出生的早产儿基本信息并进行统计学描述。结果2012-2017年德阳市出生的早产儿共13188例,其中BPD720例,发病率为5.46%;且年度发病率逐渐增长(χ2趋势=9.900,P=0.042),2017年早产儿BPD发病率6.19%显著高于2012年4.72%,差异有统计学意义(χ^2=11.501,P=0.0007);BPD在男性、胎龄较小、出生体重较低及合并新生儿窒息的早产儿中发病率较高,在早产儿母亲为外地户口、受孕方式为非自然受孕、合并胎膜早破及产道感染中发病率较高,差异有统计学意义(P<0.05)。结论BPD多发于男性、胎龄较小、出生体重较低及合并新生儿窒息的早产儿,且还与早产儿母亲户口所在地、受孕方式及是否合并胎膜早破、产道感染等因素相关。Objective To investigate the epidemiological characteristics of bronchopulmonary dysplasia( BPD) in premature infants in Deyang of Sichuan province from 2012 to 2017 and provide strategies for BPD control and prevention. Methods The basic information of the premature infants born in Deyang from 2012 to 2017 was retrospectively investigated and was statistically described. A questionnaire was designed to analyze the epidemiological characteristics of BPD. Results From 2012 to 2017,there were 13 188 premature infants born in Deyang,including 720 cases of BPD and with the incidence of 5. 46%. And the annual incidence gradually increased( χ^2 trend= 9. 900,P = 0. 042),and the incidence of BPD in premature infants in 2017 with 6. 19%,which was significantly higher than that in 2012 with 4. 72%( χ^2= 11. 501,P < 0. 05). BPD showed high morbidity in male premature infants and those with low gestational age,low birth weight and combined neonatal asphyxia,and the high morbidity of BPD was mainly concentrated on pregnant women with nonlocal accounts,unnatural conception,combined premature rupture of membranes and birth canal infections( P < 0. 05).Conclusion BPD occurs frequently in male premature infants,and those with low gestational age,low birth weight and combined neonatal asphyxia. And BPD may also be related to maternal domicile place,conception methods and the absence or presence of premature rupture of membranes and birth canal infection.

关 键 词：早产儿 支气管肺发育不良 胎龄 出生体重 

分 类 号：R181.3[医药卫生—流行病学] R722.6[医药卫生—公共卫生与预防医学]