鼓室内注射糖皮质激素治疗突发性聋的预后影响因素  

Prognostic factors in the treatment of sudden deafness via Glucocorticoid injection into tympanum

作　　者：陈敬彩[1,2] 杨军 CHEN Jing-cai;YA NG Jun(Department of Otolaryngology,the First Affiliated Hospital of Medical College of Shihezi University,Xinjiang Uygur Autonomous Region,Shihezi 832000,China;Department of Otorhinolaryngology-Head and Neck Surgery,Xinhua Hospital Affiliated to Shanghai Jiaotong University Medical College,Shanghai 200092,China)

机构地区：[1]石河子大学医学院第一附属医院耳鼻喉科,新疆石河子832000 [2]上海交通大学医学院附属新华医院耳鼻咽喉-头颈外科,上海200092

出　　处：《中国当代医药》2018年第35期7-11,共5页China Modern Medicine

基　　金：石河子大学医学院第一附属医院科研项目(YB201708)

摘　　要：目的探讨鼓室内注射糖皮质激素治疗突发性聋的预后影响因素,为临床治疗及预后判断提供依据。方法回顾性分析2017年1～12月于石河子大学医学院第一附属医院门诊或住院的97例被确诊为突发性聋患者的病历资料,将性别、年龄、发病时间、耳鸣、眩晕、合并症、听力曲线类型、听力损失程度、ABR波形分化各因素进行分组,比较各因素各组的总有效率,将对预后有影响的因素引入有序Logistic回归分析,得出影响突发性聋预后的相关因素。结果不同性别、耳鸣及合并症患者的总有效率比较,差异无统计学意义(P>0.05),不同年龄、发病时间、听力曲线类型、听力损失程度、眩晕及ABR波形分化患者的总有效率比较,差异有统计学意义(P<0.05)。Logistic回归分析结果提示,年龄、发病时间、听力曲线类型、听力损失程度、眩晕是影响突发性聋患者预后恢复的危险因素(OR=5.230、8.686、9.100、7.832、7.542,P<0.05)。结论年龄越小、发病时间越短,突发性聋预后越好,听力损失程度越重,伴眩晕,突发性聋预后越差。低中频下降型和平坦型预后较好。Objective To study prognostic factors in the treatment of sudden deafness via Glucocorticoid injection into tympanum and provide reference for clinical treatment and prognosis judgment. Methods Retrospective analysis was conducted on the medical records of 97 patients diagnosed with sudden deafness who were admitted to the outpatient department or were hospitalized of the First Affiliated Hospital of Medical College of Shihezi University from January to December 2017. Gender, age, onset time, tinnitus, vertigo, complication, hearing curve type, degree of hearing loss and ABR waveform differentiation were grouped, the total efficiency of each factor group was compared, the factors influencing the prognosis were introduced into orderly Logistic regression analysis, the related factors affecting the prognosis of sudden deafness were obtained. Results There was no statistically significant difference in the total effective rate of patients with different genders, tinnitus and complications(P>0.05). The total effective rate of patients with different age, onset time,hearing curve type, hearing loss degree, vertigo and ABR waveform differentiation were compared, and the differences were statistically significant(P<0.05). Logistic regression analysis results indicated that age, onset time, hearing curve type, hearing loss degree and vertigo were risk factors influencing the prognosis and recovery of patients with sudden deafness(OR=5.230, 8.686, 9.100, 7.832, 7.542, P<0.05). Conclusion The younger the patients with sudden deafness and the shorter onset time, the better the efficacy and prognosis are; the higher the level of hearing loss and presence of vertigo, the worse the prognosis of the patients with sudden deafness would be. It does however appear to be affected by audiogram pattern of hearing loss,which can be used to predict prognosis. The prognosis of sudden deafness appears to be better in lowmedium frequency type and flat type.

关 键 词：突发性聋 预后 糖皮质激素 鼓室 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]