高效液相色谱-质谱法测定聚碳酸酯水杯中双酚A迁移量  

Determination of migration of bisphenol A in polycarbonate cup by high performance liquid chromatography-mass spectrometry

作　　者：杨光[1] 王珊珊[1] 王佳祥[1] YANG Guang;WANG Shan-Shan;WANG Jia-Xiang(Heilongjiang Institute of Quality Supervision and Testing,Harbin 150010,China)

机构地区：[1]黑龙江省质量监督检测研究院,哈尔滨150010

出　　处：《食品安全质量检测学报》2018年第24期6410-6413,共4页Journal of Food Safety and Quality

基　　金：国家自然科学基金项目(21105125)~~

摘　　要：目的建立高效液相色谱-质谱法(high performance liquid chromatography-mass spectrometry,HPLC-MS)测定聚碳酸酯(polycarbo nate, PC)水杯中双酚A迁移量的斱法。方法选用水、4%乙酸溶液、10%乙醇和异辛烷溶液作为食品模拟液,准确量取迁移试验中得到的食品模拟液1 mL,通过0.22μm微孔滤膜后,用高效液相色谱-质谱联用仪对双酚A进行分离测定。结果该斱法相对标准偏差不大于3.24%(n=6),回收率在87.7%～105.0%之间;检出限为1μg/L。结论该斱法样品前处理斱法简便,检出限高,操作简单,线性关系好,适合于PC水杯及不同塑料制品中迁移双酚A的检测分析。Objective To establish a method for determination of the migration of bisphenol A in polycarbonate (PC)cups by high performance liquid chromatography-mass spectrometry (HPLC-MS)method.Methods Water, 4% acetic acid solution,10% ethanol and isooctane solution were used as food simulation solution.The 1mL of the food simulating solution obtained in the migration test was accurately measured,and passed through a 0.22μm microporous membrane,and the bisphenol A was separated by HPLC-MS.Results The relative standard deviations of the method were less than 3.24%(n=6),the recovery rates were 87.7%-105.0%;and the detection limit was 1μg/L. Conclusion The method has the advantages of simple sample preparation method,high detection limit,simple operation and good linear relationship,which is suitable for detection and analysis of migration of bisphenol A in PC water cups and different plastic products.

关 键 词：高效液相色谱-质谱法 聚碳酸酯水杯 双酚A 

分 类 号：O657.63[理学—分析化学] TS972.23[理学—化学]