非小细胞肺癌顺铂耐药相关长链非编码RNA研究进展  

Progress of non-small cell lung cancer cisplatin resistance associated long non-coding RNA

作　　者：龚道辉 闵凌峰 Gong Daohui;Min Lingfeng(Department of Respzratory Medicine,Clinical Medical College of Yangzhou University, Subei People's Hospital of Jangsu Province,Yangzhou 225001,China)

机构地区：[1]扬州大学医学院江苏省苏北人民医院呼吸内科,225001

出　　处：《国际呼吸杂志》2018年第24期1896-1898,共3页International Journal of Respiration

基　　金：国家自然科学基金(81302016、81302015);江苏省自然科学基金(BK20130456);江苏省六大人才高峰项目(2015-WSN-106).

摘　　要：部分长链非编码RNA(lncRNA)在肺癌发生、发展中异常表达,并直接参与调控肿瘤细胞对顺铂耐药。对国内外非小细胞肺癌(NSCLC)顺铂耐药相关lncRNA的研究进展进行综述,可能为治疗及逆转NSCLC顺铂耐药提供新的思路及突破口。Some long non-coding RNAs (lncRNA)aberrantly expressed in lung cancer,it also participated in modulating cancer cells resistant to cisplatin.The summarized progress of lncRNA which associated with cisplatin resistance in non-small cell lung cancer (NSCLC)may provide with new strategies to treat and reverse cisplatin resistance in patients with NSCLC.

关 键 词：长链非编码RNA 癌 非小细胞肺 顺铂耐药 

分 类 号：R734.2[医药卫生—肿瘤]