天麻半夏方治疗前庭性偏头痛  

Tianma Banxia recipe in the treatment of vestibular migraine

作　　者：梁雪松[1] 项颗[2] 李桦[2] 刘寅[2] 张健 孙莉[2] LIANG Xuesong;XIANG Ke;LI Hua;LIU Yin;ZHANG Jian;SUN Li(Heilongjiang University of Chinese Medicine,Harbin 150040,China;First Clinical Hospital of Jilin Academy of Traditional Chinese Medicine,Changchun 130021,China)

机构地区：[1]黑龙江中医药大学,哈尔滨150040 [2]吉林省中医药科学院第一临床医院,长春130021

出　　处：《吉林中医药》2018年第12期1390-1393,共4页Jilin Journal of Chinese Medicine

基　　金：吉林省卫生技术创新项目(2016J031)

摘　　要：目的观察天麻半夏方治疗前庭性偏头痛(风痰阻络证)的临床疗效。方法采用随机对照法将符合纳入标准的120例前庭性偏头痛(风痰阻络证)患者随机分为中药组、西药组及联合用药组,每组各40例。中药组给予中药配方颗粒天麻半夏方,西药组给予甲磺酸倍他司汀,联合用药组同时给予以上两种药物,3组疗程均为2周,比较3组治疗前后临床总疗效、眩晕残障量表(DHI)及健康状况量表(SF-36)评分情况。治疗后3个月进行随访,观察3组眩晕复发情况。结果治疗2周后联合用药组总有效率(81.1%)优于中药组(76.3%)和西药组(48.6%),差异有统计学意义(P <0.05);3组眩晕残障量表及健康状况量表评分均有改善,仅联合用药组与中药组较治疗前差异有统计学意义(P <0.05);治疗后3个月,联合用药组(5.7%)与中药组(8.6%)眩晕复发率明显低于西药组(35.3%)。结论天麻半夏方治疗前庭性偏头痛(风痰阻络证)安全、有效,能够明显改善临床症状,提高患者日常生活质量,并且在一定程度上控制眩晕复发。Objective To observe the clinical efficacy of Tianma Banxia recipe in the treatment of vestibular migraine(obstruction of collateral caused by windphlegm). Methods A randomized controlled trial of 120 patients with vestibular migraine(obstruction of collateral caused by windphlegm) who met the inclusion criteria was randomly divided into TCM group, western medicine group and combined medication group, 40 cases in each group. The TCM group was given the traditional Chinese medicine formula Tianma Banxia recipe, the western medicine group was given betahistine mesylate and the combined medication group was given the above two drugs at the same time, the three groups of treatments were all 2 weeks. The total clinical efficacy, the Dyna Disability Scale(DHI) and the Health Status Scale(SF-36) scores were compared before and after treatment, after three months, follow-up was performed to observe the recurrence of vertigo in the three groups. Results After two weeks of treatment, the total eff ective rate(81.1%) was better than that of the TCM group(76.3%) and the western medicine group(48.6%), the diff erence was statistically significant(P < 0.05). The scores of the three groups of vertigo disability and health status were improved, there was a statistically significant diff erence between the combined medication group and the TCM group(P < 0.05). Three months after treatment, the recurrence rate of vertigo in combined medication group(5.7%) and TCM group(8.6%) was significantly lower than that in western medicine group(35.3%). Conclusion Tianma Banxia recipe is safe and eff ective in treating vestibular migraine(obstruction of collateral caused by windphlegm), it can significantly improve clinical symptoms, improve the quality of daily life of patients, and control the recurrence of vertigo to some extent.

关 键 词：天麻半夏方 前庭性偏头痛 风痰阻络 

分 类 号：R255.3[医药卫生—中医内科学]