ECMO成功救治2018年广东省首例重症人感染H7N9禽流感患者  

The first case of severe avian influenza A(H7N9)in Guangdong Province in 2018 successfully treated with extracorporeal membrane oxygenation

作　　者：李建伟[1] 姜海明[1] 李斌飞[1] 梁宏开 吴桂深[1] 徐雪影[1] 侯六生[1] 陈妙莲 阮宗发 Li Jianwei;Jiang Haiming;Li Binfei;Liang Hongkai;Wu Guishen;Xu Xueying;Hou Liusheng;Chen Miaolian;Ruan Zongfa(Department of Critical Care Medicine,Zhongshan Hospital Affiliated to Sun Yat-sen University,Zhongshan 528400, Guangdong,China)

机构地区：[1]广东省中山大学附属中山医院重症医学科,广东中山528400

出　　处：《中华危重病急救医学》2018年第12期1200-1201,共2页Chinese Critical Care Medicine

基　　金：广东省社会发展领域科技计划项目(63119).

摘　　要：人感染H7N9禽流感易诱发重症急性呼吸窘迫综合征(ARDS),传统机械通气无法纠正低氧血症,患者因而死于持续低氧导致的多器官功能衰竭。体外膜肺氧合(ECMO)能提供有效的呼吸支持,可为重症H7N9的救治赢得时间。中山大学附属中山医院收治了广东省2018年首例重症H7N9患者,该患者因H7N9诱发重症ARDS,传统机械通气无法纠正低氧血症,在ECMO辅助下肺部情况逐步改善,辅助13d后成功脱离ECMO,55d后转入普通病房,102d后康复出院,出院随访2个月,患者身体健康,生活质量良好。本文详细介重症H7N9的诊治经过,为今后重症H7N9的救治提供经验。Human infection with avian influenza A(H7N9)is easy to induce severe acute respiratory distress syndrome(ARDS),and traditional mechanical ventilation cannot correct hypoxemia,so patients may die from multiple organ failure(MOF)caused by persistent hypoxia.Extracorporeal membrane oxygenation(ECMO)can provide effective respiratory support and win time for the treatment of severe H7N9.The first case of severe H7N9 in Guangdong Province in 2018 was admitted to Zhongshan Hospital Affiliated to Sun Yat-sen University.The case was insult with severe ARDS caused by H7N9,the traditional mechanical ventilation could not correct hypoxemia,and the lung condition gradually improved with ECMO assistance.After 13 days of ECMO support,the patient was successfully weaned from ECMO and was transferred to a general ward after 55 days.After 102 days of rehabilitation,the patient was discharged from hospital and followed up for 2 months,who was in good health and had a good quality of life.This article states the diagnosis and treatment of severe H7N9 in details,providing experience for the treatment of severe H7N9 in the future.

关 键 词：人感染H7N9禽流感 体外膜肺氧合 急性呼吸窘迫综合征 

分 类 号：R511.7[医药卫生—内科学]