超声造影彩色参数成像预测甲状腺乳头状癌被膜侵犯及颈部淋巴结转移的初步探讨  

Initial research for the diagnostic value of contrast-enhanced ultrasound parametric imaging in predicting extracapsular invasion and cervical lymph node metastasis of papillary thyroid cancer

作　　者：丁珂[1] 严昆[1] 崔秋丽[1] 杨薇[1] 吴薇[1] 尹珊珊[1] 刘文英[1] Ding Ke;Yan Kun;Cui Qiuli;Yang Wei;Wu Wei;Yin Shanshan;Liu Wenying(Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Department of Ultrasound,Peking University Cancer Hospital & Institute,Beijing 100142,China)

机构地区：[1]北京大学肿瘤医院暨北京市肿瘤防治研究所超声科恶性肿瘤发病机制及转化研究教育部重点实验室,100142

出　　处：《中华超声影像学杂志》2018年第12期1054-1057,共4页Chinese Journal of Ultrasonography

基　　金：首都卫生发展基金(首发2016-2-2153).

摘　　要：目的探讨甲状腺乳头状癌(papillary thyroid cancer,PTC)癌结节的超声造影彩色参数成像表现,及其预测PTC被膜侵犯及颈部淋巴结转移的临床价值。方法选取2016年1月至2017年1月于我院行超声造影彩色参数成像分析并经手术病理证实为PTC患者136例,共158个癌结节。根据手术病理结果,将癌结节分别分为被膜未侵犯组和侵犯组、颈部淋巴结未转移组和转移组,分别总结比较各组的超声造影彩色参数成像特征,分析PTC被膜侵犯及颈部淋巴结转移的危险因素。结果超声造影彩色参数成像示向心性增强模式与PTC被膜侵犯有关,差异有统计学意义(P=0.001);灌注时间在被膜侵犯组与未侵犯组间差异无统计学意义(P>0.05)。灌注时间、灌注模式在颈部淋巴结转移组与未转移组间差异无统计学意义(均P>0.05)。结论PTC癌结节超声造影彩色参数成像表现有助于预测PTC被膜侵犯,向心性增强模式更多出现被膜侵犯。Objective To study the enhanced performance of contrast-enhanced ultrasouond(CEUS)parametric imaging,and to explore the diagnostic value of CEUS parametric imaging in predicting extracapsular invasion and cervical lymph node metastasis of papillary thyroid cancer(PTC).Methods One hundred and fifty-eight PTCs in 136 patients pathologically proven papillary thyroid carcinoma between January 2016 and January 2017 were enrolled in this study.According to the pathological results of extracapsular invasion and cervical lymph node metastasis respectively,the PTCs were grouped into the negative group and the positive group.The parametric imaging features of the two groups were summarized to explore the risk factors of extracapsular invasion and cervical lymph node metastasis of PTCs respectively.Results The parametric imaging suggested that centripetal enhancement had a significant effect on extracapsular invasion(P=0.001).While there was no difference in the perfusion start time of extracapsular invasion between the negative and positive group(P>0.05).Besides,there was no statistical significance in the perfusion start time and perfusion pattern of cervical lymph node metastasis between the negative and positive group(all P>0.05).Conclusions The parametric imaging features help predicting extracapsular invasion in PTCs.And the ones with centripetal enhancement patterns are more often with extracapsular invasion.

关 键 词：超声造影 甲状腺肿瘤 淋巴结 被膜侵犯 

分 类 号：R445.1[医药卫生—影像医学与核医学] R736.1[医药卫生—诊断学]