头面部带状疱疹皮损愈合时间及遗留瘢痕的相关性  

Factors related to healing time and scarring of herpes zoster in head and face

作　　者：魏梅[1] 范文葛[1] 张青松[2] 张静[1] 薛峤[1] 赵军[1] 丁浩[1] 王玲[1] 陶晓瑜[1] Wei Mei;Fan Wenge;Zhang Qingsong;Zhang Jing;Xue Qiao;Zhao Jun;Ding Hao;Wang Ling;Tao Xiaoyu(Department of Dermatology,Changshu No.1 People's Hospital,Changshu Hospital Affiliated to Soochow University,Changshu 215500,China)

机构地区：[1]苏州大学附属常熟市第一人民医院皮肤科,215500 [2]常熟市新区医院皮肤科

出　　处：《中华医学美学美容杂志》2018年第6期441-444,共4页Chinese Journal of Medical Aesthetics and Cosmetology

摘　　要：目的探讨头面部带状疱疹皮损愈合情况和损容性后遗症的影响因素。方法选择2017年1月至2018年6月在苏州大学附属常熟市第一人民医院皮肤科诊治的头面部带状疱疹患者92例。记录皮损控制、好转、愈合时间,同时记录患者的性别、年龄、发病部位、开始治疗时间以及有无搔抓、挤压皮损、剥除痂皮行为。检测患者血糖、血清白蛋白水平;观察瘢痕的遗留情况,并进行统计分析。结果糖尿病组患者皮损控制、愈合时长分别为(2.40±1.28)d、(10.38±2.47)d,无糖尿病组分别为(1.72±0.94)d、(8.32±2.66)d,差异有统计学意义(均P<0.05)。年龄、发病部位、合并糖尿病、挤压皮损、自行剥除痂皮为头面部带状疱疹瘢痕形成的相关因素(均P<0.05)。发病部位、合并糖尿病、自行剥除痂皮为头面部带状疱疹瘢痕形成的独立危险因素(均P<0.05)。结论糖尿病影响带状疱疹皮损的愈合过程。发生于非三叉神经部位、合并糖尿病、剥除痂皮为头面部带状疱疹瘢痕形成的独立危险因素。Objective To investigate the healing degree of lesions of herpes zoster in the head and face and the risk factor of the discosmetic sequelae.Methods 92 case of herpes zoster in the head and face were enrolled in this study.The patients were treated in dermatological clinic of Changshu No.1 People's Hospital from Jan.2017 to Jun.2018.The clinical data were recorded,such as'the time of control,improving and healing of lesion,sex,age,position,the time of therapy starting and the behavior of scratching,extrusion and divest crust.The blood glucose and serum albumin of patients were measured.We observed the remained scars and performed statistic analysis.Results In diabetes group,the control and healing time was (2.40±1.28)d and (10.38±2.47)d respectively,meanwhile the control and healing time was (1.72±0.94)d and (8.32±2.66)d respectiveIy in non-diabetes group (P<0.05).The single factor analysis indicated that the age,position,diabetes,lesion extrusion,divest crust were the correlation factors of the zoster scar in head and face (P<0.05).Nevertheless the multifactor logistic regression indicated that the position,diabetes and divest crust were independent risk factors of the zoster scar in head and face (P<0.05).Conclusions The healing of herpes zoster is affected by diabetes.The independent risk factors of zoster scar in head and face are non-trigeminal nerves positions,diabetes and divest crust.

关 键 词：带状疱疹 瘢痕 危险因素 糖尿病 低白蛋白血症 

分 类 号：R752.12[医药卫生—皮肤病学与性病学]