北京朝阳医院2015—2017年HIV检测情况分析  

HIV screening tests analysis in Beijing Chaoyang hospital from 2015-2017

作　　者：冷冬[1] 朱佐民[1] 霍虹[1] 梁玉芳[1] 高志戎[1] 李桂芹[1] LENG Dong;ZHU Zuomin;HUO Hong;LIANG Yufang;GAO Zhirong;LI Guiqin(Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China)

机构地区：[1]首都医科大学附属北京朝阳医院

出　　处：《中国艾滋病性病》2018年第12期1197-1199,共3页Chinese Journal of Aids & STD

基　　金：国家自然科学基金青年项目(81700061);北京市医院管理局临床医学发展专项经费(ZYLX201805);国家临床重点专科建设项目~~

摘　　要：目的根据2015—2017年北京朝阳医院本部艾滋病病毒(HIV)检测结果,分析HIV检测结果的判断和艾滋病的流行趋势。方法用化学发光法对临床样本血清进行HIV抗原抗体联合测定,按检测规范对有反应的样本进行复检和患者基本信息采集,由北京市朝阳区疾病预防控制中心(CDC)进行HIV抗体确证试验。结果2015—2017年北京朝阳医院本部累计进行HIV检测245226例,初筛有反应性663例(初筛有反应性率2.70‰),确证阳性449例(确证阳性率1.83‰),确证阴性136例(初筛假阳性率0.55‰),确证不确定报告78例(可疑阳性率0.32‰)。三年内确证阳性病例主要为来源于皮肤(184例)、急诊(58例)、呼吸(53例)及消化内科(26例),年龄在20~40岁的男男性行为者(MSM)209例。结论20~40岁的MSM是本地区艾滋病防控干预的主要人群;假阳性病例主要来源于消化内科,提示消化道类疾病可能对此检测造成干扰。Objective To assess the results of HIV testing and the epidemic trend according to the HIV test results in the headquarter of Beijing Chaoyang hospital from 2015 to 2017.Methods Patients’ serums were tested by combined assay of HIV antigen and antibody using chemiluminescence method.According to the HIV test guideline,the serum with reaction was retested,while the patients' basic information was collected.The positive results of retested serums were submitted to Beijing Chaoyang district center for disease control (CDC) for confirmation.Results There were a total of 245 226 patients receiving HIV tests during 2015 and 2017,with 663 cases (2.70‰) of screened HIV positive,449 cases (1.83) confirmed as HIV positive,136 cases (0.55‰) as HIV negative,and 78 cases (0.32‰) having uncertain results.The confirmed positive cases were mainly from the departments of dermatology (184 cases) ,emergency (58 cases),respiratory (53 cases) and gastroenterology (26 cases) ,who were between 20-40 years old with 209 cases of MSM infected with HIV.Conclusion MSM between 20-40 years old are the main group of HIV infection,who need more intervention of HIV prevention and control in the future.The main source for the HIV false positive by the ABBOTT chemiluminescence is the patients from department of gastroenterology,suggesting that digestive diseases may interfere with HIV detection.

关 键 词：艾滋病 化学发光 筛查 疾病控制 

分 类 号：R512.91[医药卫生—内科学]