活血化瘀法对活动期SLE患者凝血指标的影响  

Effect of the Promoting Blood Circulation for Removing Blood Stasis Method on Blood Coagulation Indexes in Patients with Active Systemic Lupus Erythematosus

作　　者：朱盈盈[1] ZHU Yingying(Integrated Department,Zhongshan Hospital Affiliated to Guangzhou University of Chinese Medicine,Guangdong Province,Zhongshan 528400,China)

机构地区：[1]广州中医药大学附属中山医院综合科,广东中山528400

出　　处：《光明中医》2018年第12期1722-1724,共3页GUANGMING JOURNAL OF CHINESE MEDICINE

摘　　要：目的观察活血化瘀法对活动期SLE患者体内的凝血指标改变及临床意义。方法选择40例活动期SLE患者进行研究,对40例患者使用活血化瘀中药,连续治疗4周,治疗前后检测采用ELISA法检测其血浆F1+2、抗心磷脂抗体(ACA)及血浆AT-Ⅲ活性进行比较研究。结果与治疗前相比,治疗后血浆F1+2浓度明显下降,血浆AT-Ⅲ活性明显升高(P<0.05)。血浆F1+2浓度及血浆AT-Ⅲ活性改变在ACA阳性及ACA阴性患者中同期比较,其差异无统计学意义(P>0.05)。结论活血化瘀法对改善活动期SLE患者高凝状态有一定作用。Objective To observe the promoting blood circulation for removing blood stasis method on the changes and clinical significance of blood coagulation in patients with active stage systemic,lupus erythematosus (SLE ).Methods 40 cases of active SLE patients were studied,and all of them used promoting blood circulation for removing blood stasis method and treatment of 4 weeks.The plasma F1+2 level,anti cardiolipin antibody (ACA)and plasma AT-Ⅲ level of patient before and after treatment were detected.Results After treatment,plasma F1+2 level decreased significantly and plasma AT-Ⅲ level significantly increased (P<0.05).In same period,the plasma formula 1+2 and plasma AT-Ⅲ level change in ACA positive and ACA negative patients was compared,and the difference was not statistically significant (P>0.05).Conclusion Using the promoting blood circulation for removing blood stasis method is helpful to improve the hypercoagulant state of SLE patients.

关 键 词：活血化瘀法 凝血酶原片段1+2 AT-Ⅲ 系统性红斑狼疮 高凝状态 

分 类 号：R259[医药卫生—中西医结合]