益气利水方对气虚水停型心衰BNP及LVEF的影响  

Effect of Benefiting Qi and Inducing Diuresis Prescription on the BNP and LVEF of Retention of Body Fluid Due to Qi Deficiency of Heart Failure

作　　者：吴怡萍[1] 蔡少杭[1] WU Yiping;CAI Shaohang(Department of Cardiology,Zhangzhou Hospital of Traditional Chinese Medicine,Fujian Province,Zhangzhou 363000,China)

机构地区：[1]福建省漳州市中医院心血管科,漳州363000

出　　处：《光明中医》2017年第15期2188-2191,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

基　　金：福建中医药大学校管课题项目(No.XB2016056)

摘　　要：目的观察益气利水方对气虚水停型心衰患者临床症状及BNP、心脏彩超射血分数水平影响,评估益气利水方临床疗效,探讨其在气虚水停型心衰上的治疗价值。方法将符合纳入标准的60例心衰(气虚水停型)患者进行随机化分组,对照组、试验组各30例。对照组患者进行西医规范化心衰治疗,试验组患者在对照组治疗基础上加用益气利水方。4周治疗后对比两组患者用药前后临床症状及BNP、EF水平变化情况,所得数据经统计学相关分析。结果治疗4周后西医症状疗效比较,试验组总有效率为86.7%,对照组为60.0%,P<0.05。中医症状疗效比较,试验组总有效率为90.0%,对照组为66.7%,P<0.05。两组患者治疗前后BNP水平均较治疗前降低,试验组降低幅度优于对照组;治疗后两组患者EF较治疗前升高,试验组升高幅度优于对照组。结论益气利水方能够有效降低心衰患者BNP水平,提高射血分数水平,改善气虚水停型心衰患者的临床症状及生活质量。Objective To observe the clinical symptom and effect of benefiting qi and inducing diuresis prescription on the BNP and LVEF of retention of body fluid due to qi deficiency of heart failure,to evaluate the clinical curative,and to discuss the therapeutic value.Methods 60 cases of patients with chronic heart failure (retention of body fluid due to deficiency of qi)were divided into control group and experimental group,with 30 cases in each group..The control group was given the conventional Western medicine treatment.The experimental group was given the Western medicine combined with benefiting qi and inducing diuresis prescription.Four weeks after treatment,the BNP level,EF level and clinical features was compared.Results Four weeks after Western medicine treatment,the total effective rate of the experimental group and the control group was 86.7% and 60.0%,respectively P <0.05.Four weeks after TCM treatment,the total effective rate of the experimental group and the control group was 90.0% and 66.7%,respectively P <0.05.After treatment,BNP levels were significantly lower than those before treatment,and reduction rate of the experimental group was better than that of the control group.After treatment,EF of the two groups elevated,and the amplitude of the experimental group was higher than of the control group.Conclusion The benefiting qi and inducing diuresis prescription could effectively enhance clinical effect for CHF patient, reduce the plasma BNP concentration,and improve ejection fraction level,clinical symptom and quality of life.

关 键 词：益气利水方 气虚水停型 心衰 BNP 

分 类 号：R541.6[医药卫生—心血管疾病]