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作 者:无 黄跃生 吕国忠[3] The Burn and Trauma Branch of Chinese Geriatrics Society;Huang Yuesheng;Lyu Guozhong(State Key Laboratory of Trauma,Burns and Combined Injury,Institute of Burn Research,the First Affiliated Hospital of Army Medical University (the Third Military Medical University), Chongqing 400038;Department of Burns and Plastic Surgery,the Third People's Hospital of Wuxi City, Wuxi 214041)
机构地区:[1]中国老年医学学会烧创伤分会 [2]陆军军医大学(第三军医大学)第一附属医院全军烧伤研究所,创伤、烧伤与复合伤国家重点实验室,重庆400038 [3]江苏省无锡市第三人民医院烧伤整形科,214041
出 处:《中华损伤与修复杂志(电子版)》2018年第6期406-409,共4页Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)
基 金:无锡贝迪生物工程股份有限公司的支持
摘 要:胶原是人体主要的结构蛋白,在伤口愈合过程中具有重要作用。以胶原为原料的材料因其天然的止血性、良好的生物相容性、较低的免疫原性及可控的生物降解性等性能,备受人们关注。本文主要介绍了胶原类创面材料的特点、作为支架材料和创面覆盖物应用的机制,并就其临床适应证、推荐使用方法、禁忌证以及注意事项等形成较为规范、统一的专家共识,以帮助临床医师和患者正确认识并合理使用胶原类创面材料。Collagen,as the main structural protein in human body,plays an important role in the wound healing process.Due to their inherent hemostatic characteristics,good biocompatibility,low immunogenicity,as well as controllable biodegradability,collagen-based materials have attracted much attention.In this article,we mainly introduce the characteristics of collagen-based wound biomaterials and the application mechanism as scaffold and wound dressing.And the standard and unified experts'consensus formed on the clinical indications,recommended applications,contraindications,and matters needing attention.The consensus wound help clinicians and patients to recognize collagen-based wound biomaterials correctly and use them rationally.
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