人参、红参、西洋参3种配方颗粒的傅里叶变换红外光谱快速鉴别方法  

Rapid Identification for 3 formula granules of Ginseng, Red Ginseng and American Ginseng by FT-IR

作　　者：范帅帅[1] 高晗 田伟[1,3,4] 彭新华 牛丽颖 FAN Shuaishuai;GAO Han;TIAN Wei;PENG Xinhua;NIU Liying(Hebei University of Chinese Medicine,Shijiazhuang 05009i,China;Hebei TCM Formula Granule Engineering & Technology Research Center,Shijiazhuang 050091,China;TCM Formula Granule Research Center of Hebei Province University,Shijiazhuang 050091,China;Shineway Pharmaceutical Group Ltd.,Shijiazhuang 051430,China)

机构地区：[1]河北中医学院,河北石家庄050091 [2]神威药业集团有限公司,河北石家庄051430 [3]河北省中药配方颗粒工程技术研究中心,河北石家庄050091 [4]河北省高校中药配方颗粒应用技术研发中心,河北石家庄050091

出　　处：《药物评价研究》2018年第12期2242-2247,共6页Drug Evaluation Research

基　　金：河北省中医药管理局科研计划项目(2017015)

摘　　要：目的建立人参、红参、西洋参3种配方颗粒的傅里叶变换红外光谱快速鉴别方法。方法采用红外光谱及其二阶导数光谱、二维相关光谱,分析不同配方颗粒的红外光谱特征。结果傅里叶变换红外光谱能够从整体上反映化学成分的不同情况,二阶导数光谱和二维相关光谱在800～1800 cm-1能够对不同配方颗粒进行不同程度的区分,二维相关光谱的区分效果明显。结论通过综合比较傅里叶变换红外光谱、二阶导数光谱和二维相关光谱,可以准确、快速鉴别人参、红参、西洋参3种配方颗粒。Objective To establish a rapid FT-IR method for identifying 3 Formula Granules of Ginseng,Red Ginseng and American Ginseng.Methods FT-IR alongwith corresponding second derivative spectra and two-dimensional correlation spectra were applied to analyze different Formula Granules of Ginseng,Red Ginseng and American Ginseng.Results FT-IR holistically demonstrated the different chemical features.In the range of 800~1800 cm^-1,the second-derivative spectra and two-dimensional correlation spectra effectively distinguished different Formula Granules,between which the latter was superior.Conclusion By comprehensively comparing the FT-IR and corresponding second derivative spectra and two-dimensional correlation spectra,identification for 3 Formula Granules of Ginseng,Red Ginseng and American Ginseng could be realized rapidly and accurately.

关 键 词：傅里叶红外光谱 二阶导数光谱 二维相关光谱 人参 红参 西洋参 配方颗粒 

分 类 号：R917[医药卫生—药物分析学]