胰岛素控制妊娠期糖尿病血糖对妊娠结局的影响分析  

Effect analysis of insulin-controlled blood glucose in gestational diabetes mellitus on pregnancy outcome

作　　者：王惠兰 WANG Hui-lan(Rushan People's Hospital,Rushan 264500,China)

机构地区：[1]乳山市人民医院,264500

出　　处：《中国实用医药》2019年第2期20-21,共2页China Practical Medicine

摘　　要：目的探讨妊娠期糖尿病患者实施胰岛素控制血糖对其妊娠结局的影响。方法 180例妊娠期糖尿病患者,按随机数字表法分为实验组与对照组,各90例,对照组实施常规治疗,实验组实施胰岛素控制治疗,对比两组患者血糖指标水平、妊娠不良结局以及新生儿不良结局。结果实验组患者治疗后空腹血糖、餐后1 h血糖、餐后2 h血糖、糖化血红蛋白水平分别为(4.01±0.24)mmol/L、(6.81±0.62)mmol/L、(5.62±0.55)mmol/L、(5.65±1.04)%,均低于对照组的(4.83±0.41)mmol/L、(8.43±0.95)mmol/L、(7.36±0.75)mmol/L、(8.81±1.22)%,差异均有统计学意义(P<0.05)。实验组妊娠不良结局发生率为11.11%,低于对照组的27.78%,差异有统计学意义(P<0.05)。实验组新生儿不良结局发生率为8.89%,低于对照组的20.00%,差异有统计学意义(P<0.05)。结论妊娠期糖尿病患者实施胰岛素控制血糖,对患者妊娠结局的影响显著,可以明显改善其血糖水平,改善其妊娠结局,值得临床推广借鉴。Objective To discuss the effect of insulin-controlled blood glucose in gestational diabetes mellitus on pregnancy outcome. Methods A total of 180 gestational diabetes mellitus patients were divided by random number table into experimental group and control group, with 90 cases in each group. The control group received conventional therapy, and the experimental group received insulin-controlled therapy. Comparison were made on blood glucose level, adverse pregnancy outcomes and adverse neonatal outcomes between the two groups. Results After the experimental group had fasting blood glucose, postprandial 1 h blood glucose, postprandial 2 h blood glucose and glycosylated hemoglobin level respectively as(4.01±0.24) mmol/L,(6.81±0.62) mmol/L,(5.62±0.55) mmol/L and(5.65±1.04)%, which were all lower than(4.83±0.41) mmol/L,(8.43±0.95) mmol/L,(7.36±0.75) mmol/L and(8.81±1.22)% in the control group, and their difference was statistically significant(P<0.05). The experimental group had lower incidence of adverse pregnancy outcome as 11.11% than 27.78% in the control group, and the difference was statistically significant(P<0.05). The experimental group had lower incidence of adverse neonatal outcomes as 8.89% than 20.00% in the control group, and the difference was statistically significant(P<0.05). Conclusion The implementation of insulin-controlled blood glucose in patients with gestational diabetes shows a significant effect on the pregnancy outcome of patients, and it can significantly improve their blood glucose levels and pregnancy outcomes. It is worthy of clinical promotion and reference.

关 键 词：胰岛素控制 妊娠期糖尿病 血糖 妊娠结局 

分 类 号：R714.256[医药卫生—妇产科学]