IDEAL-IQ对多囊卵巢综合征患者与健康女性颈部锁骨上、肝脏及皮下脂肪的对照研究  

The Preliminary Study Of Supraclavicular Adipose Tissue、Liver and Subcutaneous Adipose Tissue In PCOS And Healthy Women With IDEAL-IQ

作　　者：常红花 赵红翠[1] 于洋[1] 袁慧书[1] CHANG Honghua;ZHAO Hongeui;YU Yang(Peking University Third Hospital,Beijing 100191 ,P.R.China)

机构地区：[1]北京大学第三医院放射科,100191 [2]北京医院放射科

出　　处：《临床放射学杂志》2018年第12期2063-2067,共5页Journal of Clinical Radiology

摘　　要：目的探讨IDEAL-IQ评估多囊卵巢综合征(PCOS)患者与健康女性颈部锁骨上、肝脏及皮下脂肪的差异性。方法 50例PCOS患者(20^35岁)及按年龄匹配的87名健康女性志愿者,行3.0T磁共振扫描,分别测量颈部锁骨上、腹壁皮下脂肪及肝脏的脂肪分数(FF),分别分析两组颈部锁骨上脂肪与腹壁皮下脂肪FF的差异性以及两组颈部锁骨上、腹壁皮下脂肪及肝脏的组间差异。结果 PCOS患者和健康女性志愿者颈部锁骨上FF(80.99±7.73)%、(87.38±7.06)%均低于腹壁皮下脂肪FF(91.17±2.00)%、(92.52±2.23)%(P<0.05);体质指数(BMI)<24组,PCOS患者颈部锁骨上FF(83.20±7.22)%高于健康女性(79.13±7.09)%,两者组间有显著差异(P=0.017),PCOS患者肝脏FF(3.57±3.41)%高于健康女性(1.83±0.70)%,两者组间有显著差异(P=0.000),PCOS患者和健康女性志愿者腹壁皮下脂肪FF组间无明显差异(P=0.443);BMI≥24组,PCOS与健康女性志愿者颈部锁骨上脂肪、肝脏和腹壁皮下脂肪FF均无明显差异(P=0.287、0.129、0.613)。结论 BMI正常的PCOS患者锁骨上脂肪较健康女性更接近于皮下白色脂肪,可能存在脂代谢异常,IDEAL-IQ提供了一种无创检测脂代谢异常的方法。Objective To assess the difference of supraclavicular adipose tissue 、liver and subcutaneous adipose tissue in PCOS and healthy women with IDEAL-IQ.Methods 50 patients with PCOS(20-35 years old) and 87 normal female volunteers matched for age underwent 3.0 T MRI scan in the study.Fat fraction(FF) was measured respectively on supraclavicular adipose tissue 、liver and abdominal wall subcutaneous adipose tissue.We analyzed the difference of FF between supraclavicular adipose tissue and abdominal wall subcutaneous adipose tissue separately and analyze the difference of FF between the two groups on supraclavicular adipose tissue、liver and abdominal wall subcutaneous adipose tissue between PCOS patients and healthy women.Results FF of supraclavicular adipose tissue(80.99±7.73、87.38±7.06) % was lower than FF of abdominal wall subcutaneous adipose tissue(91.17±2.00、92.52±2.23) %(P<0.05).In the group of BMI<24,the FF of supraclavicular adipose tissue(83.20±7.22) % in PCOS patients was higher than that in healthy women(79.13±7.09) %,there was a significant difference between the two groups(P=0.017);The FF of liver(3.57±3.41) % in PCOS patients was higher than that in healthy women(1.83±0.70) %,there was a significant difference between the two groups(P=0.000);FF of abdominal wall subcutaneous adipose tissue had no significant difference between PCOS patients and healthy women(P=0.443).In the group of BMI≥24,FF of supraclavicular adipose tissue 、liver and abdominal wall subcutaneous adipose tissue had no significant difference between PCOS patients and healthy women(P=0.287、0.129、0.613).Conclusion Supraclavicular adipose tissue of PCOS Patients with normal BMI is closer to the subcutaneous white adipose tissue than that of healthy women,who may have abnormal lipid metabolism.IDEAL-IQ provides a non-invasive method to detect abnormal lipid metabolism.

关 键 词：多囊卵巢综合征 锁骨上脂肪 棕色脂肪 白色脂肪 

分 类 号：R711.75[医药卫生—妇产科学] R445.2[医药卫生—临床医学]