可见光诱导下喹喔啉-2(1H)-酮与重氮盐的直接C—H 3-芳基化反应（英文）  

Direct C—H 3-Arylation of Quinoxalin-2(H)-ones with Aryl Diazonium Salts under Visible-Light Irradiation

作　　者：王雷雷 鲍鹏丽 刘维维 刘思彤 胡昌松 岳会兰[2] 杨道山 魏伟[1,2] Wang Leilei;Bao Pengli;Liu Weiwei;Liu Sitong;Hu Changsong;Yue Huilan;Yang Daoshan;Wei Wei(School of Chemistry and Chemical Engineering,Qufu Normal University,Qufu 273165;Key Laboratory of Tibetan Medicine Research,Northwest Institute of Plateau Biology, Chinese Academy of Sciences,Xining 810008)

机构地区：[1]曲阜师范大学化学与化工学院,曲阜273165 [2]中国科学院西北高原生物研究所中国科学院藏药研究重点实验室,西宁810000

出　　处：《有机化学》2018年第12期3189-3196,共8页Chinese Journal of Organic Chemistry

基　　金：Supported by the Natural Science Foundation of Shandong Province(Nos.ZR2018MB009,ZR2016JL012);the International Cooperation Project of Qinghai Province(Nos.2018-HZ-806,2017-HZ-806);the National Natural Science Foundation of China(Nos.21302109,21302110)~~

摘　　要：发展了一种简单、实用可见光诱导喹喔啉-2(1H)-酮与重氮盐的直接C—H 3-芳基化反应.该反应采用便宜Eosin Y为催化剂,可以在室温、空气下高效完成3-芳基喹喔啉-2(1H)-酮的构建.该方法不需要任何金属试剂、碱、酸和强氧化剂,为3-芳基喹喔啉-2(1H)-酮提供一个价格便宜、操作简便的合成方法.A simple and practical visible-light-induced protocol has been developed for the construction of 3-arylquinoxalin-2(1H)-ones via Eosin Y-catalyzed direct C-H 3-arylation of quinoxalin-2(H)-ones with aryl diazonium salts at room temperature in air. The present reaction provides a cost-effective and operationally straightforward approach to the target products in moderate to good yields, and does not require any metal reagents, bases, acids, and strong oxidants.

关 键 词：可见光 EOSIN Y催化 C-H芳基化 重氮盐 3-芳基喹喔啉-2(1H)-酮 

分 类 号：O621.25[理学—有机化学]