钯催化烯烃的分子内氟芳基化反应（英文）  

Palladium-Catalyzed Intramolecular Fluoroarylation of Alkenes

作　　者：杨文铖 亓晓旭 陈品红[1] 刘国生[1] Yang Wencheng;Qi Xiaoxu;Chen Pinhong;Liu Guosheng(State Key Laboratory of Organometallic Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032)

机构地区：[1]中国科学院上海有机化学研究所金属有机化学国家重点实验室分子合成科学卓越创新中心

出　　处：《有机化学》2019年第1期122-128,共7页Chinese Journal of Organic Chemistry

基　　金：Project supported by he National Key R&D Program of China(973 Program,No.2015CB856600);the National Natural Science Foundation of China(Nos.21532009,21672236,21761142010,21790330);the Science Technology Commission of the Shanghai Municipality(Nos.17QA1405200,17JC1401200);the Chinese Academy Sciences(Nos.XDB20000000,QYZDJSSW-SLH055);the Youth Innovation Promotion Association(No.2018292)~~

摘　　要：发展了一种钯催化的烯烃分子内氟芳基化反应,以ArIF2作为氟源和亲电试剂来活化烯烃,实现了4-芳基-1-丁烯的氟化关环反应,以中等到良好的收率得到氟芳基化产物.这类反应为从烯基芳烃出发合成氟代四氢萘和氟代色满提供了高效方法.A novel palladium-catalyzed intramolecular fluoroarylation of alkenes has been developed, in which ArIF2 was employed as fluorine source as well as I(Ⅲ) reagent to activate olefin, to deliver the fluoroarylation products from 4-aryl- 1-olefins in moderate to good yields. The current transformation presents a convenient method to provide fluorotetralins and fluorochromanes under mild conditions from alkenes tethered arenes.

关 键 词：钯催化 烯烃 氟芳基化 四氢萘 

分 类 号：O621.251[理学—有机化学]