中西医结合治疗对甲状腺功能亢进患者甲状腺上动脉血流动力学的影响  

Effect of Traditional Chinese Combined with Western Medicine on Hemodynamics of Superior Thyroid Artery in Patients with Hyperthyroidism

作　　者：邬文景[1] 郑珏如[2] 沈俊晔[3] 魏秀芝[1] 胡晶晶 王珏[1] 付淑萍[1] WU Wenjing;ZHENG Jueru;SHEN Junye;WEI Xiuzhi;HU Jingjing;WANG Jue;FU Shuping(Department of Doppler Ultrasonic,Ningbo Second Hospital,Ningbo 315000,Zhejiang,China;Thyroid Surgery Department,Ningbo Second Hospital,Ningbo 315000,Zhejiang,China;Traditional Chinese Medicine Department,Ningbo Second Hospital,Ningbo 315000,Zhejiang,China)

机构地区：[1]宁波市第二医院超声科,浙江宁波315000 [2]宁波市第二医院甲状腺外科,浙江宁波315000 [3]宁波市第二医院中医科,浙江宁波315000

出　　处：《中华中医药学刊》2019年第1期213-216,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省中医药科技计划项目(2017ZA123);宁波市第二医院"华美研究基金"项目(2017HMKY19)

摘　　要：目的:分析与探讨采用中西医结合治疗对甲状腺功能亢进患者的临床疗效,并研究彩色多普勒超声对甲状腺上动脉血流动力学的评价。方法:将2015年11月—2017年11月期间诊疗94例甲状腺功能亢进患者作为研究病例,采用数字表法根据用药治疗方案不同分成两组,每组47例。对照组给予常规西药他巴唑治疗,观察组给予他巴唑联合中药自拟嘱方治疗。观察两组甲状腺功能功能情况、甲状腺上动脉血流动力学变化情况以及临床治疗效果。结果:观察组治疗后TSH(4.95±1.51)mIU/L、TRAb(3.04±1.03)U/L、V_(max)(0.37±0.07)m/s、V_(min)(0.16±0.02)m/s、临床总有效率(93.62%)等均明显优于对照组TSH(4.18±1.85)mIU/L、TRAb(4.71±1.02)U/L、V_(max)(0.57±0.11)m/s、V_(min)(0.34±0.04)m/s、临床总有效率(76.60%),差异有统计学意义(P<0.05)。两组不良反应发生情况比较无差异(P>0.05)。结论:采用中西医结合治疗甲状腺功能亢进的患者,能够促进其甲状腺功能相关指标恢复,彩色多普勒超声观察患者甲状腺上动脉血流动力学指标显著改善,甲状腺明显缩小,临床应用效果较好,有助于患者预后。Objective: To analyze and discuss the clinical efficacy of integrated traditional Chinese and Western medicine in the treatment of hyperthyroidism and evaluate the hemodynamics of superior thyroid artery by color Doppler ultrasound.Methods: From November 2015 to November 2017, 94 patients with hyperthyroidism treated in our hospital were enrolled in the study.They were divided into two groups based on the digital table method and 47 cases in each group.The control group was treated with conventional western medicine tazopazole and the observation group was treated with triazole combined with Chinese medicine.The thyroid glands function, the hemodynamic changes of the superior thyroid artery and the effect of clinical treatment of the two groups were observed.Results: After treatment,the observation group's TSH(4.95±1.51)mIU/L, TRAb(3.04±1.03)U/L, Vmax(0.37±0.07)m/s, Vmin(0.16±0.02)m/s and the total clinical efficiency(93.62%)were significantly better than the control group's TSH(4.18±1.85)mIU/L, TRAb(4.71±1.02)U/L, Vmax(0.57±0.11)m/s, Vmin(0.34±0.04)m/s and the total clinical efficiency(76.60%), and the difference was statistically significant(P<0.05).There was no difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion: Traditional Chinese medicine combined with western medicine treatment of hyperthyroidism can promote the recovery of relevant indicators of thyroid function.The color Doppler ultrasound showed patients' thyroid artery hemodynamic parameters improved significantly, thyroid significantly reduced.It has good clinical effect, contribute to the prognosis of patients.

关 键 词：血流动力学 中西医 甲状腺功能亢进 动脉 彩色多普勒超声 

分 类 号：R581.1[医药卫生—内分泌]