从热毒辨治亚急性甲状腺炎急性期临床疗效  

Treatment and Sydnrome Differentiation for Acute Phase of Subacute Thyroiditis from Heat

作　　者：都静[1] 张晓明[2] 吴姗姗[1] DU Jing;ZHANG Xiaoming;WU Shanshan(Liaoning University Hospital of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China;The Third Affiliated Hospital of Traditional Chinese Medicine,Shcnyang 110000,Liaoning,China)

机构地区：[1]辽宁中医药大学附属医院,辽宁沈阳110032 [2]辽宁中医药大学附属第三医院,辽宁沈阳110000

出　　处：《中华中医药学刊》2019年第1期236-238,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：辽宁省科技计划项目(20170540595)

摘　　要：目的:探讨从热毒辨治亚急性甲状腺炎急性期的临床疗效观察。方法:选择2015年1月—2016年1月医院亚急性甲状腺炎患者72例,按照随机随机数字表发分为观察组和对照组,每组各36例,治疗组采用中药治疗以清热解毒为治疗大法,佐以理气化痰祛湿,对照组采用阿司匹林合用泼尼松治疗。统计并对比分析两组患者临床疗效、不良反应、复发率情况。结果:观察组36例患者,治疗总有效率94.4%,明显高于对照组治疗总有效率77.8%,两组比较有统计学差异(P<0.05);两组在甲状腺肿消退时间、疼痛消失时间、疗程有显著性差异;对照组患者恶心呕吐者、头痛等不良反应发生率为16.7%,观察组的不良反应发生率2.8%;观察组明显低于对照组,两组比较有统计学差异(P<0.05);治疗后随访12个月,观察组复发率为2.8%明显低于对照组的19.4%,两组比较有显著性差异(P<0.05)。结论:清热解毒之法在亚急性甲状腺炎急性期有良好的临床疗效,且不良反应发生率和复发率低,值得临床推广应用。Objective: To study the clinical effect of the treatment of acute phase of subacute thyroiditis from heat.Methods: Between January 2015 and January 2016,52 cases of subacute thyroiditis patients,according to the stochastic random number table were divided into observation group and control group,each group 26 patients.The observation group was treated by traditional Chinese medicine with heat-clearing and detoxifying treatment,helping with expelling phlegm and dampness method.The control group used aspirin and prednisone.We analyzed two groups' clinical efficacy,adverse reaction and recurrence rate.Results: The observation group's total effective rate was 94.4%,significantly higher than the control group's 77.8%.The two groups were statistically significant( P < 0.05).Control group's incidence of adverse reactions like nausea and vomiting and headache was 16.7% and that of the treatment gorup was 2.8%.The observation group's was significantly lower than that of the control group and there was a statistical significance( P <0.05).After followed up for 12 months after treatment,the recurrence rate was 2.8% in the observation group was obviously lower than the control group's 19.4% and the two groups had significant difference( P < 0.05).Conclusion: The method of heat-clearing and detoxifying in the acute phase of subacute thyroiditis has good clinical efficacy,and the incidence of adverse reactions and the recurrence rate is low,worthy of popularization and application.

关 键 词：亚急性甲状腺炎 清热解毒 临床观察 

分 类 号：R581.4[医药卫生—内分泌]